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Anti-IgLON5 Disease 10 Years Later: What We Know and What We Do Not Know.
Neurol Neuroimmunol Neuroinflamm
January 2025
Service of Neurology, Hospital Clinic, Barcelona, Spain.
Anti-IgLON5 disease was identified 10 years ago, thanks to the discovery of IgLON5 antibodies and the joint effort of specialists in sleep medicine, neuroimmunology, and neuropathology. Without this collaboration, it would have been impossible to untangle fundamental aspects of this disease. After the seminal description in 2014, today there is growing evidence that most patients present a chronic progressive course with gait instability, abnormal movements, bulbar dysfunction, and a sleep disorder characterized by nonrapid eye movement and REM parasomnias, and obstructive sleep apnea with stridor.
View Article and Find Full Text PDFAssociation of vertigo with adult obstructive sleep apnea: A systematic review and meta-analysis.
Sleep Med
December 2024
Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan; Center of Sleep Disorder, National Taiwan University Hospital, Taipei, Taiwan; Department of Otolaryngology, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:
Background: Several studies have demonstrated a relationship between vertigo and obstructive sleep apnea (OSA) in adults. This review examined the association between vertigo and OSA and investigated the effects of OSA treatment on vestibular function.
Methods: Searches were conducted in PubMed, MEDLINE, EMBASE, Cochrane, Scopus, and Web of Science databases.
Assessing the impact of apnea duration on the relationship between obstructive sleep apnea and hearing loss.
PLoS One
December 2024
Department of Otorhinolaryngology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Objectives: The relationship between obstructive sleep apnea (OSA) and hearing loss (HL) remains uncertain. This study aimed to investigate the relationship between OSA and HL, and to identify which factors play a key role.
Methods: A retrospective review was conducted of 90 subjects diagnosed with OSA.
Waiting for in-Lab Polysomnography May Unnecessarily Prolong Treatment Start in Patients with Moderate or Severe OSA at Home Sleep Apnea Testing.
Nat Sci Sleep
December 2024
Department of Otolaryngology, Head and Neck Surgery & Sleep Medicine Center, University Medical Center Mainz, Mainz, 55131, Germany.
Purpose: The gold standard in obstructive sleep apnea (OSA) diagnostics is nocturnal full-night polysomnography (PSG). Due to high costs and high time effort portable respiratory polygraphy (PG or home sleep apnea testing-HSAT) has been developed. In contrast to PG the PSG gains relevant further information concerning sleep stages, arousals and leg movements.
View Article and Find Full Text PDFEffects of Tobacco Use on the Macrostructure and Microstructure of Sleep in Patients with OSA.
Nat Sci Sleep
November 2024
The Second Clinical College of Fujian Medical University, Quanzhou, Fujian Province, 362000, People's Republic of China.
Article Synopsis
- The study investigates how tobacco use impacts sleep quality in patients with obstructive sleep apnea (OSA), analyzing data from 1017 hospitalized patients over three years.
- Findings show that tobacco users with OSA experienced significantly worse sleep quality, marked by longer light sleep and less deep sleep (N3), while the severity of tobacco dependence did not correlate with sleep quality.
- The results suggest that tobacco use adversely affects sleep structure in OSA patients, with greater disruptions in those with more severe OSA.
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