The antifungal activity of extracts obtained from Piper regnellii with supercritical carbon dioxide was tested against yeast and filamentous fungi. The most active extract was obtained from leaves extracts of P. regnellii at 40°C and 25 MPa, featuring a minimal inhibitory concentration of 3.9 μg/mL against Trichophyton mentagrophytes. Neolignans eupomatenoid-3, eupomatenoid-5, eupomatenoid-6 and conocarpan were present in all extracts. The results indicate the possibility of further studies on the use of extracts of P. regnellii obtained by supercritical extraction, as potential sources of bioactive compounds for use in medicine.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2013.830215 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of antifungal activity of extracts of Piper regnellii obtained by supercritical fluid extraction.
Nat Prod Res
September 2014
a Programa de Pós-graduação em Engenharia Química, Universidade Estadual de Maringá , Maringá , Brazil.
The antifungal activity of extracts obtained from Piper regnellii with supercritical carbon dioxide was tested against yeast and filamentous fungi. The most active extract was obtained from leaves extracts of P. regnellii at 40°C and 25 MPa, featuring a minimal inhibitory concentration of 3.
View Article and Find Full Text PDFAnti-tuberculosis neolignans from Piper regnellii.
Phytomedicine
May 2013
Postgraduate Program in Pharmaceutical Sciences, State University of Maringá, Maringá, Paraná, Brazil.
The present study determined the anti-Mycobacterium tuberculosis activities of supercritical CO2 extracts, neolignans eupomatenoid-5 (1), conocarpan (4) and eupomatenoid-3 (7) and their derivatives (2, 3, 5, 6, and 8) from Piper regnellii, as well as their cytotoxicities. The supercritical CO2 extract from leaves was purified by chromatographic methods, yielding compounds (1), (4) and (7), which were identified by (1)H NMR and comparison with literature data. Anti-M.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!