AI Article Synopsis

  • Aerosolized therapies have been utilized in clinical settings for many years, with innovations leading to the development of therapies like aerosolized insulin, antibiotics, and chemotherapy.
  • Various factors influence the efficacy and safety of these therapies, including how aerosols are produced, how they spread in the lungs, and how the body defends itself against them.
  • The presentation will cover current aerosol production methods, the body’s respiratory defenses, evaluation techniques for aerosol therapies, and future opportunities for their development in medicine.

Article Abstract

Aerosolized therapies have been used in everyday clinical practice for decades. Experimentation with different delivery systems have led to the creation of aerosolized insulin, antibiotics, gene therapy and chemotherapy. Several of these therapies are already clinically available while others are being investigated in active clinical trials. The main factors affecting the efficiency and safety of the aerosolized therapies are the production of the aerosol, distribution/deposition of the aerosol throughout the lung parenchyma, respiratory defense mechanisms and tissue/pharmaceutical molecule interactions. Current methods of aerosol production and distribution will be presented along with an overview of the respiratory defense mechanisms. In addition, methods of aerosol evaluation in conjunction with a future perspective of the potential development of aerosol therapies will be presented.

Download full-text PDF

Source
http://dx.doi.org/10.2174/157340641130900041DOI Listing

Publication Analysis

Top Keywords

defense mechanisms
12
aerosol production
8
aerosolized therapies
8
respiratory defense
8
methods aerosol
8
will presented
8
aerosol
6
mechanisms respiratory
4
respiratory system
4
system aerosol
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!