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Challenges in intraoperative differentiation of craniopharyngioma and Rathke cleft cyst on endoscopic visualization.
J Clin Neurosci
January 2025
Department of Neurosurgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Background: Craniopharyngiomas are epithelial tumors derived from the remnants of the Rathke pouch, while Rathke cleft cysts (RCC) are benign cystic lesions originating from the Rathke pouch itself [1]. Rathke cleft cysts comprise 10-15% of the hypophyseal tumors, while craniopharyngiomas are relatively rare, comprising only 2-5% of intracranial tumors [2]. Both located in the sellar and parasellar regions and share clinical symptoms including headache, visual disturbances, and endocrine dysfunction [3].
View Article and Find Full Text PDFClinical response to dabrafenib plus trametinib in BRAF V600E mutated papillary craniopharyngiomas: a case report and literature review.
Front Oncol
November 2024
Beaumont Hospital, Beaumont Health, Royal Oak, MI, United States.
Papillary craniopharyngiomas are rare tumors prevalent to the precision oncology world due to their high rate of BRAF V600E mutations. Symptoms include vision loss, neuroendocrine dysfunction, and cognitive dysfunction. Treatment involves an interdisciplinary approach with surgery, radiation, and systemic treatment.
View Article and Find Full Text PDFEndoscopic endonasal resection of a craniopharyngioma in a 23-month-old patient: illustrative case.
J Neurosurg Case Lessons
December 2024
Departments of Neurological Surgery, University of Washington, Seattle, Washington.
Background: Treatment of pediatric craniopharyngioma requires a multidisciplinary approach to counsel patients and families on the spectrum of treatment options, including biopsy, radiation, and/or resection. Gross-total resection can avoid radiation and its long-term comorbidities. In very young patients, this is of particular importance but is especially challenging because of anatomical considerations.
View Article and Find Full Text PDFA rare case of intratumoral hemorrhage in a young adult with adamantinomatous craniopharyngioma.
Radiol Case Rep
January 2025
Department of Pathological Anatomy, Faculty of Medicine, University of Padjadjaran, Dr. Hasan Sadikin General Hospital, Jl. Pasteur No. 38, Pasteur, Sukajadi, Bandung City, West Java 40161, Indonesia.
Craniopharyngiomas are rare, slow growing tumors arising along the craniopharyngeal duct. The incidence of craniopharyngioma was 0.13 per 100,000 persons per year.
View Article and Find Full Text PDFExpanded endoscopic endonasal approach to a retrochiasmatic craniopharyngioma with significant retroclival cystic extension.
J Clin Neurosci
January 2025
Department of Neurosurgery, The Royal Melbourne Hospital, Melbourne, Victoria, Australia; Department of Surgery, The University of Melbourne, Melbourne, Victoria, Australia.
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