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Cardamonin anticancer effects through the modulation of the tumor immune microenvironment in triple-negative breast cancer cells.
Am J Cancer Res
December 2024
Division of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University Tallahassee, FL 32307, The United States.
The tumor immune microenvironment (TIME) plays a critical role in cancer development and response to immunotherapy. Immune checkpoint inhibitors aim to reverse the immunosuppressive effects of the TIME, but their success has been limited. Immunotherapy directed at PD-1/PD-L1 has been widely employed, yielding positive results.
View Article and Find Full Text PDFSuccessful Treatment of Growing Skull Fracture That Developed Only 3 Weeks After Injury: A Case Report.
Korean J Neurotrauma
December 2024
Department of Neurosurgery, Dankook University Hospital, Cheonan, Korea.
A growing skull fracture (GSF) is a fracture that gradually widens as the arachnoid membrane or brain parenchyma herniates into the fractured space in a skull fracture accompanied by dural injury. GSF has a good prognosis if diagnosed early and treated surgically. However, it is generally a chronic complication with low incidence, making diagnosis difficult.
View Article and Find Full Text PDFPrimary Intra-operative Embolisation During Urgent Parallel Graft Endovascular Repair in Paravisceral Symptomatic Aortic Pseudoaneurysm.
EJVES Vasc Forum
November 2024
Vascular Surgery, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Objective: Paravisceral aortic lesions present significant challenges for endovascular treatment. This retrospective analysis of consecutively treated patients from April 2017 to June 2021 aimed to analyse the outcome of primary intra-operative embolisation of aortic complicated pseudoaneurysms and gutter channels during parallel graft (PG) repair of paravisceral symptomatic aortic pseudoaneurysms.
Methods: Patients with symptomatic pseudoaneurysms of the paravisceral aorta treated with PGs using chimney or periscope configurations were included.
Hydroperiod Influences Tadpole Growth and Development in the Endangered Littlejohn's Tree Frog ().
Ecol Evol
January 2025
Conservation Science Research Group, School of Environmental and Life Sciences University of Newcastle Callaghan New South Wales Australia.
Amphibians are among the most threatened vertebrate taxa globally. Their global decline necessitates effective conservation actions to bolster populations across both the larval and adult stages. Constructing man-made ponds is one action proven to enhance reproduction in pond-breeding amphibians.
View Article and Find Full Text PDFWarming associated with climate change is driving poleward shifts in the marine habitat of anadromous Pacific salmon ( spp.). Yet the spawning locations for salmon to establish self-sustaining populations and the consequences for the ecosystem if they should do so are unclear.
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