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Therapeutic potential of nicorandil beyond anti-anginal drug: A review on current and future perspectives.
Heliyon
April 2024
Department of Pharmacology, Therapeutics & Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Idi-Araba, P.M.B. 12003 Lagos, Nigeria.
Nicorandil (NIC) is a well-known anti-anginal agent, which has been recommended as one of the second-line treatments for chronic stable angina as justified by the European guidelines. It shows an efficacy equivalent to that of classic anti-anginal agents. NIC has also been used clinically in various cardiovascular diseases such as variant or unstable angina and reperfusion-induced damage following coronary angioplasty or thrombolysis.
View Article and Find Full Text PDF[Ulcers in vulva and perineum induced by an anti-anginal drug].
Ugeskr Laeger
May 2022
Abdominalcenteret, Københavns Universitetshospital - Bispebjerg Hospital.
Nicorandil is a type of nicotinamide ester used for the treatment of angina and ischaemic heart disease. A 67-year-old woman was referred to a pelvic floor unit with possible vulvar cancer. She had a painful 2 × 1.
View Article and Find Full Text PDFNon-healing parastomal ulcer: think nicorandil.
ANZ J Surg
December 2021
General Surgery Department, Rockhampton Hospital, Rockhampton, Queensland, Australia.
Nicorandil's adverse effects can cause severe patient morbidity and can present to any specialty. Those with underlying diverticular disease are most susceptible. Medication reviews are vital for patients presenting with ulcer or fistula symptoms.
View Article and Find Full Text PDFPainful perianal ulcers with nicorandil.
BMJ
September 2020
West Midlands Centre for Adverse Drug Reactions, City Hospital, Birmingham, UK.
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