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Antioxidant activity, phytochemical composition, and antitumor capacity of Amazonian fruits taperebá (Spondias mombin) and murici (Byrsonima crassifolia).
Arch Pharm (Weinheim)
January 2025
Program in Food and Nutrition, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil.
The Amazon rainforest is renowned for its biodiversity and as a reservoir of edible and medicinal plants. The phytochemicals in murici and taperebá fruits serve as natural antioxidants, contributing to cultural preservation, ecosystem protection, and economic opportunities. However, limited scientific research on their composition and health benefits hinders their recognition as functional foods.
View Article and Find Full Text PDFEffect of Antimicrobial Wipes on Hospital-Associated Bacterial and Fungal Strains.
Infect Chemother
December 2024
Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea Seoul, Korea.
Background: Healthcare-associated infections (HAI) caused by multidrug-resistant organisms have emerged as a significant global issue, posing substantial challenges to healthcare systems. Low- and intermediate-level disinfectants are extensively utilized for cleaning and disinfecting surfaces in hospitals to mitigate environmental transmission of HAI. Therefore, the need for more effective and environmentally safe disinfectants is increasing.
View Article and Find Full Text PDFMetabolomics analyses and comparative insight to neuroprotective potential of unripe fruits and leaves of Citrus aurantium ethanolic extracts against cadmium-induced rat brain dysfunction: involvement of oxidative stress and akt-mediated CREB/BDNF and GSK3β/NF-κB signaling pathways.
Metab Brain Dis
January 2025
Pharmacognosy Department, National Research Centre (NRC), El Behouth St., P.O. 12622, Cairo, Egypt.
Serious neurological disorders were associated with cadmium toxicity. Hence, this research aimed to investigate the potential neuroprotective impacts of the ethanolic extracts of Citrus aurantium unripe fruits and leaves (CAF and CAL, respectively) at doses 100 and 200 mg/kg against cadmium chloride-provoked brain dysfunction in rats for 30 consecutive days. HPLC for natural pigment content revealed that CAF implied higher contents of Chlorophyll B, while the CAL has a high yield of chlorophyll A and total carotenoid.
View Article and Find Full Text PDFDiversification of Lipopeptide Analogues Drives Versatility in Biological Activities.
J Agric Food Chem
January 2025
Instituto de Hortofruticultura Subtropical y Mediterránea La Mayora, Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Microbiología, Universidad de Málaga, Málaga 29071, Spain.
Article Synopsis
- Cyclic lipopeptides (CLPs) are important secondary metabolites with different biological activities, primarily produced in three families: iturins, fengycins, and surfactins, each consisting of cyclic peptides attached to fatty acids.
- The study focused on isolating and analyzing various CLP variants from the strain UMAF6639, testing their effects on antifungal activity and promoting plant growth, revealing that both these effects depend on the specific lipopeptide variant and its concentration.
- The research highlights a balance in the abundance and toxicity of these variants, showing that less abundant toxic variants can work synergistically with more abundant, less toxic ones, while also contributing to increased bacterial populations and bioactivity, which could lead to sustainable agricultural
Isolated Foot Drop Due to a Cerebral Infarction Mimicking Lumbar Radiculopathy: A Case Report and Literature Review.
Cureus
January 2025
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Isolated foot drop is a neurological sign frequently linked to lower motor neuron (LMN) lesions, including peroneal nerve damage or L4-L5 radiculopathy. Nonetheless, upper motor neuron (UMN) lesions, such as strokes or tumors located in the parasagittal motor cortex, may sometimes manifest as isolated foot drops. The main causes of isolated foot drop secondary to central etiologies are uncommon, with few instances documented in the literature.
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