Factor analytic models are widely used in social sciences. These models have also proven useful for sparse modeling of the covariance structure in multidimensional data. Normal prior distributions for factor loadings and inverse gamma prior distributions for residual variances are a popular choice because of their conditionally conjugate form. However, such prior distributions require elicitation of many hyperparameters and tend to result in poorly behaved Gibbs samplers. In addition, one must choose an informative specification, as high variance prior distributions face problems due to impropriety of the posterior distribution. This article proposes a default, heavy-tailed prior distribution specification, which is induced through parameter expansion while facilitating efficient posterior computation. We also develop an approach to allow uncertainty in the number of factors. The methods are illustrated through simulated examples and epidemiology and toxicology applications. Data sets and computer code used in this article are available online.
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http://dx.doi.org/10.1198/jcgs.2009.07145 | DOI Listing |
Indian J Crit Care Med
November 2024
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Unlabelled: Adequately powered randomized controlled trials (RCTs) are considered the highest level of evidence in guiding clinical practice. Reports using Bayesian hypothesis-testing to reanalyze RCTs are increasing. One distinct advantage of Bayesian analysis is that we can obtain a range of numerical probabilities that reflect how likely a study intervention is more effective than the alternative after considering both pre-existing available evidence and the alternate hypotheses.
View Article and Find Full Text PDFAdv Med Educ Pract
January 2025
Department of Pediatrics, The University of Jordan, Amman, Jordan.
Background: During COVID-19 pandemic in Jordan, a number of medical students participated in voluntary work. However, barriers and facilitators were unclear. Therefore, we aimed to evaluate their experience and attitudes towards volunteering during a pandemic and the factors affecting that.
View Article and Find Full Text PDFParasit Vectors
January 2025
Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Liverpool, UK.
Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. They pose a significant risk to public health with over 200 million cases of malaria per annum and approximately 4 billion people at risk of arthropod-borne viruses (arboviruses). Mosquito populations are geographically expanding into temperate regions and their distribution is predicted to continue increasing.
View Article and Find Full Text PDFValue Health
January 2025
RTI Health Solutions, Manchester, UK. Electronic address:
Objectives: Several trial-level surrogate methods have been proposed in the literature. However, often only one method is presented in practice. By plotting trial-level associations between surrogate and final outcomes with prediction intervals and by presenting results from cross-validation procedures, this research demonstrates the value of comparing a range of model predictions.
View Article and Find Full Text PDFArq Bras Oftalmol
January 2025
Department of Ophthalmology & Visual Sciences, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Purpose: To evaluate if color Doppler can detect internal blood flow in circumscribed choroidal hemangioma.
Methods: This cross-sectional study examined seven eyes of seven participants with circumscribed choroidal hemangiomas, with or without prior treatment. B-scan ultrasound and color Doppler were used to assess the dimensions, topographical distribution, and internal blood flow of the affected eyes.
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