Severe refractory asthma: an update.

Eur Respir Rev

Dept of Respiratory Medicine, Academic Medical Centre, Amsterdam, The Netherlands.

Published: September 2013

AI Article Synopsis

  • Asthma is a complex disease that not everyone can control effectively with existing treatments, leading to a group classified as "severe refractory" asthma.
  • There have been improvements in defining this severe form of asthma and developing systematic ways to evaluate and classify patients, which helps in giving the right treatment.
  • New targeted therapies are being developed to enhance treatment outcomes, symptoms, and overall quality of life for these patients.

Article Abstract

Asthma is a heterogeneous disease in which adequate asthma control cannot be achieved in a substantial proportion despite currently available treatment possibilities. This subgroup has been defined as "severe refractory" asthma. Over the past years considerable progress has been made regarding a more exact definition of severe refractory asthma. A systematic approach to evaluate the asthma patient has been postulated. Further detailed classification into distinct phenotypes is ongoing to target the right treatment to the right patient. And, new therapeutic targeted treatment options are currently in development to provide possible new targets to improve disease state, symptoms and quality of life. This review will provide an update on the latest advancements with regard to all these domains.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487365PMC
http://dx.doi.org/10.1183/09059180.00001913DOI Listing

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