Time to positivity of blood cultures in neonates.

Pediatr Infect Dis J

From the *Department of Paediatrics and †Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, Udupi, Karnataka, India.

Published: February 2014

Blood culture reports in neonatal sepsis aid physician in either optimizing therapy or discontinuing antibiotics. We determined the time taken for neonatal blood cultures to become positive using the aerobic BacT/Alert system. Of 944 blood cultures from 816 neonates, 139 (14.7%) were positive. Growth of all definitive bacteria, 95% of possible bacteria and 84% of fungi were detected within 48 hours of incubation.

Download full-text PDF

Source
http://dx.doi.org/10.1097/INF.0000000000000018DOI Listing

Publication Analysis

Top Keywords

blood cultures
12
time positivity
4
blood
4
positivity blood
4
cultures neonates
4
neonates blood
4
blood culture
4
culture reports
4
reports neonatal
4
neonatal sepsis
4

Similar Publications

Background: Febuxostat and topiroxostat are non-purine selective xanthine oxidoreductase inhibitors commonly used for hyperuricaemia treatment in Japan. However, comparative data on the effects of febuxostat and topiroxostat on renal function and proteinuria are limited. This study compared proteinuria incidence and changes in the estimated glomerular filtration rate (eGFR) among prevalent febuxostat and topiroxostat users.

View Article and Find Full Text PDF

Blood transfusion plays a vital role in modern medicine, but frequent shortages occur. Ex vivo manufacturing of red blood cells (RBCs) from universal donor cells offers a potential solution, yet the high cost of recombinant cytokines remains a barrier. Erythropoietin (EPO) signaling is crucial for RBC development, and EPO is among the most expensive media components.

View Article and Find Full Text PDF

The blood-brain barrier (BBB) is a specialized network that maintains central nervous system homeostasis. Disruption of the BBB can lead to neuronal damage and contribute to neurodegenerative diseases like Parkinson's disease (PD), characterized by alpha-synuclein (αSN) aggregation, which forms intracellular inclusions. Mesenchymal stem cells (MSCs) have shown promise in alleviating the severity of neurological diseases through their paracrine secretions.

View Article and Find Full Text PDF

A randomised non-inferiority trial investigating antibiotic adjustments based on blood culture in acute cholangitis.

Clin Microbiol Infect

January 2025

Department of internal medicine and liver research institute, Seoul national university hospital, Seoul national university college of medicine, Seoul, Republic of Korea. Electronic address:

Objectives: This study evaluated the adequacy of using blood cultures alone for antibiotic therapy in mild-to-moderate acute cholangitis after adequate biliary drainage.

Methods: A prospective, multi-centre, non-inferiority, randomised trial was conducted from August 2015 to September 2023 across 12 tertiary hospitals in South Korea. Patients were randomly assigned 1:1 to groups.

View Article and Find Full Text PDF

[Traveler's diarrhea].

Dtsch Med Wochenschr

February 2025

Traveler's diarrhea is a common and, in most cases, self-limiting illness among long-distance travelers. Pathogen diagnostics are indicated for severe or dysenteric courses as well as for increased risk of severe courses. A central component of pathogen diagnostics is stool culture.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!