AI Article Synopsis
- A study examined 20 cases of pituitary microadenoma using PET scans with FDG, focusing on 17 cases of Cushing disease and 3 of acromegaly.
- PET yielded 12 positive results compared to 7 positives from CT and 13 positives from MR imaging, highlighting its effectiveness in identifying tumors.
- Unlike traditional imaging methods, which showed false positives in healthy individuals, PET did not yield any false positives among 20 control subjects, indicating its superior specificity.
Article Abstract
Twenty cases of surgically verified pituitary microadenoma (17 with Cushing disease and three with acromegaly) were studied with positron emission tomography (PET) with use of fluorine-18-2-fluorodeoxyglucose (FDG). The diagnostic results were compared with those of other modalities, namely, computed tomography (CT), magnetic resonance (MR) imaging, and, in the cases of Cushing disease, simultaneous bilateral inferior petrosal sinus sampling (SIPS). The PET results showed 12 positive readings and one questionable reading, compared with seven positive readings and one questionable reading for CT (18 cases studied) and 13 positive and two questionable MR imaging readings. PET complemented MR imaging, in the sense that five of the positive PET readings were negative or questionable at MR imaging. PET studies of 20 healthy control subjects showed no false-positive cases, whereas other studies of healthy subjects with contrast material-enhanced CT and MR imaging have yielded, respectively, 20% and 15% positive readings, with findings suggestive of silent or occult adenomas.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1148/radiology.177.1.2399336 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!