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Drug-induced enterocolitis syndrome in children: report of two cases and a literature review.
Turk J Pediatr
February 2025
Department of Pediatric Immunology and Allergy, Dr. Sami Ulus Maternity Child Health and Diseases Training and Research Hospital, Ankara, Türkiye.
Background: Drug-induced enterocolitis syndrome (DIES) is a recently defined clinical entity, first described in 2014. DIES is a hypersensitivity reaction with non-IgE mechanisms involving the gastrointestinal tract, occurring 1 to 4 hours after drug ingestion. Antibiotics are most commonly responsible, particularly amoxicillin or amoxicillin / clavulanic acid (AMX/CL).
View Article and Find Full Text PDFSesquiterpenoid isolated from derived from : isolation, structure elucidation, and biological activity.
Nat Prod Res
March 2025
Department of Chemistry, Faculty of Science and Informatics, Universitas Jenderal Achmad Yani, Cimahi, Indonesia.
The aim of this research was isolation, structure elucidation, and biological activities of terpenoids from endophytic fungus obtained from . An endophytic fungus, , was isolated from the roots of was cultivated and extracted to give the crude extract. The crude extract was fractionated using vacuum liquid chromatography followed by separation and purification with column chromatography to obtain a terpenoid derivative (12.
View Article and Find Full Text PDFUropathogen profiles and their antimicrobial resistance patterns in patients: a three-year retrospective study in Sichuan region.
Front Public Health
March 2025
Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China.
Background: Urinary tract infection (UTI) is the most common infection requiring empiric antibiotic treatment. Due to the increased antibiotic resistance of uropathogens and their regional variation, monitoring pathogen distribution and antimicrobial susceptibility is important to ensure effective antibiotic therapy. This retrospective study analyzed the 3-year-long uropathogen profiles and their resistance from a single tertiary general hospital (single-center) and 28 hospitals (multi-center) to provide data allowing guidance for appropriate empiric antimicrobial treatment for UTI.
View Article and Find Full Text PDFValue of ultrasound‑guided puncture combined with GeneXpert MTB/RIF technology in the diagnosis of pleural tuberculosis.
Exp Ther Med
April 2025
Department of Ultrasound, Shandong Public Health Clinical Center, Shandong University, Jinan, Shandong 250013, P.R. China.
The aim of the present study was to analyze the pathological and laboratory findings of pleural lesions post ultrasound-guided biopsy and to assess the diagnostic utility of percutaneous ultrasound-guided puncture combined with GeneXpert (MTB)/resistance to rifampin (RIF) in pleural tuberculosis (TB) diagnosis. A retrospective analysis was conducted on 46 patients who underwent ultrasound-guided biopsy at the Shandong Public Health Clinical Center (Shandong Chest Hospital) between April 2018 and April 2021. Of these, 27 patients were diagnosed with pleural TB, while 19 were confirmed to have non-pleural TB.
View Article and Find Full Text PDFAntimicrobial and cytotoxic activities of natural (Z)-13-docosenamide derived from .
Front Cell Infect Microbiol
March 2025
Department of Botany and Microbiology, Faculty of Science, Zagazig University, Zagazig, Egypt.
Introduction: The synthesis of natural compounds with strong biological activity from affordable sources has proven challenging for scientists. As a natural resource rich in a variety of bioactive substances, fungal metabolites have the potential to be used in medical applications to serve a global purpose towards a sustainable future.
Methods: A total of 25 filamentous fungi were isolated, and their secondary metabolites were assessed for their antimicrobial efficiency.
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