An easily-made Annexin-V modified quartz crystal microbalance (QCM) sensor was constructed for the quantitative detection of early stage apoptosis for the first time, achieving the goals of specific capture and sensitive detection of target cells in one step without the need for cell labelling.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3an01150j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A CRISPR-HITI strategy approach to improve CHO cell viability by modifying the 3'UTR of Caspase 8 Associated Protein 2.
Mol Biol Res Commun
January 2025
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Chinese Hamster Ovary (CHO) cells are essential in biopharmaceutical manufacturing. Scientists use CRISPR to enhance productivity. mRNAs contain UTRs that regulate gene expression, affecting protein abundance.
View Article and Find Full Text PDFModulation of signature cancer-related genes in oral cancer cells (Ca9-22) by anethole treatment: Insights into therapeutic potential.
PLoS One
December 2024
Faculté de Médecine Dentaire, Groupe de Recherche en Ecologie Buccale, Université Laval, Québec, QC, Canada.
To explore an alternative strategy to chemotherapy to combat oral cancer, natural products and their derivates constitute one promising approach. In the last previous study, we have demonstrated the potential anti-tumor properties of anethole; an aromatic compound abundantly present in nature that serves as a major active ingredient found in plants like anise and fennel. In the current study, we aimed to investigate how this molecule inhibits oral cancer cell proliferation and induces apoptosis.
View Article and Find Full Text PDFAnticancer Properties of Garlic and Ginger Extract in Colon Cancer Cell Line.
Asian Pac J Cancer Prev
November 2024
Animal Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Egypt.
Colon cancer typically affects older adults, though it can happen at any age. Colon cancer, also known as Caco-2, is caused by multiple epigenetic alterations and involves unregulated proliferation, differentiation, and invasion of neighboring tissues. Colon cancer patients have had surgery, radiation, hormone therapy, and chemotherapy.
View Article and Find Full Text PDFBackground & Aims: Transarterial chemoembolization (TACE) is the most common treatment for hepatocellular carcinoma (HCC) worldwide; however, response rates and durability vary widely. With the growing armamentarium of therapies for HCC patients, identifying predictors of response to TACE has become increasingly important for a patient population with limited hepatic reserve. We hypothesized that a distinct metabolic phenotype associated with β-catenin pathway mutations render HCC tumors more susceptible to TACE-induced ischemia.
View Article and Find Full Text PDFTargeted Delivery of Celastrol by GA-Modified Liposomal Calcium Carbonate Nanoparticles to Enhance Antitumor Efficacy Against Breast Cancer.
Pharmaceutics
October 2024
Engineering Research Center for Medicine, College of Pharmacy, Harbin University of Commerce, Harbin 150028, China.
Background/objectives: Breast cancer, a leading health threat affecting millions worldwide, requires effective therapeutic interventions. Celastrol (CEL), despite its antitumor potential, is limited by poor solubility and stability. This study aimed to enhance CEL's efficacy by encapsulating it within glycyrrhizic acid (GA)-modified lipid calcium carbonate (LCC) nanoparticles for targeted breast cancer therapy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!