A Cu(i)-catalyzed azide-alkyne cycloaddition reaction (CuAAC) has been utilized to prepare novel triazole-linked cationic porphyrin-psoralen conjugates that exhibited significant photocytotoxicity against A549 cancer cells (IC50 = 84 nM).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3ob41224e | DOI Listing |
Publication Analysis
Top Keywords
porphyrin-psoralen conjugates
8
novel porphyrin-psoralen
4
conjugates synthesis
4
synthesis dna
4
dna interaction
4
interaction cytotoxicity
4
cytotoxicity studies
4
studies cui-catalyzed
4
cui-catalyzed azide-alkyne
4
azide-alkyne cycloaddition
4
Similar Publications
Novel porphyrin-psoralen conjugates: synthesis, DNA interaction and cytotoxicity studies.
Org Biomol Chem
October 2013
Department of Chemistry, Birla Institute of Technology & Science, Pilani-333 031, India.
A Cu(i)-catalyzed azide-alkyne cycloaddition reaction (CuAAC) has been utilized to prepare novel triazole-linked cationic porphyrin-psoralen conjugates that exhibited significant photocytotoxicity against A549 cancer cells (IC50 = 84 nM).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!