AI Article Synopsis
- Inverted papillomas (IP) are usually benign tumors found in the sinuses, with up to 4% prevalence, but they can sometimes grow aggressively and become malignant.
- A case study is presented involving a 69-year-old woman whose IP rapidly invaded surrounding structures, including the orbit and skull base, and transformed into an invasive carcinoma within 3 months.
- Despite the initial benign histology of the papilloma, close endoscopic monitoring is essential for detecting possible malignant transformation, as conventional surgical methods may fail due to fast recurrence.
Article Abstract
Inverted papillomas (IP) are considered benign lesions with a prevalence up to 4% among all sinunasal tumors; however, invasive growth and varying tendency for malignization are reported in literature. We report the case of a 69-year-old woman suffering from a large, aggressively growing IP invading the orbit, skull base, and frontal lobe of the brain. Within only 3 months' time the papilloma showed transformation into an invasive carcinoma, leaving surgical therapy in vain due to explosive recurrence. Intracranial and intraorbital expansion by IP is possible despite histology not showing signs of malignancy initially. In "regular" IP close endoscopic follow-up is mandatory to not overlook recurrence harboring malignancy.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743604 | PMC |
| http://dx.doi.org/10.1055/s-0031-1280738 | DOI Listing |
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