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Botanical agents for the treatment of nonmelanoma skin cancer. | LitMetric

Botanical agents for the treatment of nonmelanoma skin cancer.

Dermatol Res Pract

University of Utah, School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132, USA.

Published: August 2013

AI Article Synopsis

  • Nonmelanoma skin cancers, mainly basal cell carcinoma and squamous cell carcinoma, are prevalent globally and are the most common types of cancer in the U.S.
  • Standard treatment usually involves surgical removal, but there's growing interest in using topical botanical alternatives for prevention and treatment, focusing on superficial skin cancer variants.
  • Botanicals, derived from various plant sources, have beneficial properties such as antioxidant and anti-inflammatory effects, positioning them as potential agents for preventing or reversing skin cancer development.

Article Abstract

Nonmelanoma skin cancers, including basal cell carcinoma and squamous cell carcinoma, are common neoplasms worldwide and are the most common cancers in the United States. Standard therapy for cutaneous neoplasms typically involves surgical removal. However, there is increasing interest in the use of topical alternatives for the prevention and treatment of nonmelanoma skin cancer, particularly superficial variants. Botanicals are compounds derived from herbs, spices, stems, roots, and other substances of plant origin and may be used in the form of dried or fresh plants, extracted plant material, or specific plant-derived chemicals. They possess multiple properties including antioxidant, anti-inflammatory, and immunomodulatory properties and are, therefore, believed to be possible chemopreventive agents or substances that may suppress or reverse the process of carcinogenesis. Here, we provide a review of botanical agents studied for the treatment and prevention of nonmelanoma skin cancers.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741697PMC
http://dx.doi.org/10.1155/2013/837152DOI Listing

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