In the 1950s, sensory deprivation research emerged as an influential new field for behavioral science researchers, supported by the intelligence community. Within a few years, deprivation research had become ubiquitous; images of sensory deprivation were invoked to explain a wide range of phenomena, from religious revelations to the very structure of psychoanalysis. Yet within a decade and a half, this field of research became implicated in cases of torture and abuse. This article examines the history of University of Manitoba psychologist John Zubek, who remained one of the final researchers still conducting sensory deprivation research in the 1970s. It raises questions on how might it be possible to successfully and cautiously perform controversial research.
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http://dx.doi.org/10.1002/jhbs.21631 | DOI Listing |
Neuroimage
January 2025
Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada; Department of Physiology, McGill University, Montreal, Quebec, Canada. Electronic address:
In response to sensory deprivation, the brain adapts to efficiently navigate a modified perceptual environment through a process referred to as compensatory crossmodal plasticity, allowing the remaining senses to repurpose deprived regions and networks. A mechanism that has been proposed to contribute to this plasticity involves adaptations within subcortical nuclei that trigger cascading effects throughout the brain. The current study uses 7T MRI to investigate the effect of perinatal deafness on the volumes of subcortical structures in felines, focusing on key sensory nuclei within the brainstem and thalamus.
View Article and Find Full Text PDFCircuit dysfunction in autism may involve a failure of homeostatic plasticity. To test this, we studied parvalbumin (PV) interneurons which exhibit rapid homeostatic plasticity of intrinsic excitability following whisker deprivation in mouse somatosensory cortex. Brief deprivation reduces PV excitability by increasing Kv1 current to increase PV spike threshold.
View Article and Find Full Text PDFElife
January 2025
Department of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Dendrites are crucial for receiving information into neurons. Sensory experience affects the structure of these tree-like neurites, which, it is assumed, modifies neuronal function, yet the evidence is scarce, and the mechanisms are unknown. To study whether sensory experience affects dendritic morphology, we use the ' arborized nociceptor PVD neurons, under natural mechanical stimulation induced by physical contacts between individuals.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
To myelinate axons, oligodendrocyte precursor cells (OPCs) must stop dividing and differentiate into premyelinating oligodendrocytes (preOLs). PreOLs are thought to survey and begin ensheathing nearby axons, and their maturation is often stalled at human demyelinating lesions. Lack of genetic tools to visualize and manipulate preOLs has left this critical differentiation stage woefully understudied.
View Article and Find Full Text PDFIran J Public Health
December 2024
Department of Social Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Background: Sensory impairments, notably hearing loss (68% in those aged 70+) and vision loss (24%-50%), are prevalent in older individuals. We investigated the correlation between visual and hearing impairments in older adults, considering sociodemographic factors, mental health, and social support.
Methods: The study is part of The Serbian 2019 National Health Survey, conducted in 2019.
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