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Perceptual decoupling in the sustained attention to response task is indeed unlikely: a reply to Shelat and Geisbrecht (in press).
Exp Brain Res
March 2025
Department of Psychology, George Mason University, 4400 University Drive, 3F5, Fairfax, VA, 22030, USA.
Shelat and Geisbrecht (in press) challenge Bedi et al.'s (Exp Brain Rese 242(8):2033-2040 2024b) position that perceptual decoupling in the Sustained Attention to Response Task (SART) is unlikely. Instead they argue perceptual decoupling is likely in the SART and advocate for the SART's continued use in perceptual decoupling research.
View Article and Find Full Text PDFPost-thrombotic syndrome (PTS) is a heterogenous chronic condition that can develop after deep vein thrombosis (DVT) and is diagnosed using the Villalta scale. This study applied unsupervised machine learning to investigate the heterogeneity of PTS among patients and within the Villalta scale. In 818 patients from the IDEAL-DVT study, clustering identified four distinct clinical profiles: (1) younger patients with provoked DVT, (2) women with joint pain, (3) men with isolated popliteal DVT, and (4) older men with diabetes and femoral vein involvement.
View Article and Find Full Text PDFUntangling the Role of MYC in Sarcomas and Its Potential as a Promising Therapeutic Target.
Int J Mol Sci
February 2025
Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.
MYC plays a pivotal role in the biology of various sarcoma subtypes, acting as a key regulator of tumor growth, proliferation, and metabolic reprogramming. This oncogene is frequently dysregulated across different sarcomas, where its expression is closely intertwined with the molecular features unique to each subtype. MYC interacts with critical pathways such as cell cycle regulation, apoptosis, and angiogenesis, amplifying tumor aggressiveness and resistance to standard therapies.
View Article and Find Full Text PDFNavigating the maze of active ageing measurement: untangling methodological and theoretical issues in the UJACAS questionnaire.
Aging Clin Exp Res
March 2025
Department of Humanities, Social Sciences and Education, University of Molise, Campobasso, Italy.
Active Ageing (AA) involves maintaining engagement in physical, social, and mental activities in older adulthood, reflecting societal values and political agendas. Despite various measurement tools, there is no universal standard. The University of Jyväskylä Active Ageing Scale (UJACAS) is increasingly used in Europe but faces inconsistencies from varying response scales across versions.
View Article and Find Full Text PDFWhose sleep matters? Untangling the relationships between maternal sleep, child sleep, and maternal depressive symptoms in the first two years of life.
Eur Child Adolesc Psychiatry
March 2025
Harvard T.H. Chan School of Public Health, Harvard University, 677 Huntington Avenue, Boston, MA, 02115, USA.
Infants frequently experience sleep problems in early childhood. Poor infant sleep can impact not only infants' cognitive development but also maternal sleep and maternal mental health. Studies have reported associations between infant sleep and maternal sleep and between infant sleep and maternal depression.
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