Damage diagnosis for turbine rotors plays an essential role in power plant management. Ultrasonic non-destructive examinations (NDEs) have increasingly been utilized as an effective tool to provide comprehensive information for damage diagnosis. This study presents a general methodology of damage diagnosis for turbine rotors using three-dimensional adaptive ultrasonic NDE data reconstruction techniques. Volume reconstruction algorithms and data fusion schemes are proposed to map raw ultrasonic NDE data back to the structural model of the object being examined. The reconstructed volume is used for automatic damage identification and quantification using region-growing algorithms and the method of distance-gain-size. Key reconstruction parameters are discussed and suggested based on industrial experiences. A software tool called AutoNDE Rotor is developed to automate the overall analysis workflow. Effectiveness of the proposed methods and AutoNDE Rotor are explored using realistic ultrasonic NDE data.
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http://dx.doi.org/10.1016/j.ultras.2013.07.019 | DOI Listing |
J Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Faculty of Medicine, Azad Tehran University of Medical Sciences, Tehran, Iran.
Background: Pedicle screw insertion in posterior spinal surgery can cause vascular injuries, including rare intercostal artery pseudoaneurysms, which are typically discovered incidentally during reimaging. Onyx embolization is an effective treatment for small artery pseudoaneurysms.
Observations: A 36-year-old man who had initially presented with back pain that remained unresponsive to nonsteroidal anti-inflammatory drugs was diagnosed with a T7-8 sarcomatous lesion confirmed by magnetic resonance imaging and biopsy.
J Med Chem
January 2025
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China.
To date, the abuse of antibiotics and a gradual decline in novel antibiotic discovery enlarge the threat of drug-resistant bacterial infections, especially methicillin-resistant (MRSA). Herein, inspired by the unique structures and antibacterial activities of 2-quinolones, a class of novel 2-quinolones with substituted pyridines was synthesized. Notably, compound , the derivative with a methylpyridine fragment, showed potent antibacterial and antibiofilm activities, especially for MRSA strains (MIC = 0.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, South Korea.
Background: The oocyte retrieval is a critical step in assisted reproductive technologies, including in vitro fertilization and fertility preservation. Despite evolving techniques, the optimal aspiration pressure during retrieval remains debatable, with limited in vivo human studies. Existing studies, primarily in vitro and on animals, suggest that inappropriate aspiration pressures can impair oocyte quality.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Kidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
METTL3, a key enzyme in N6-methyladenosine (m6A) modification, plays a crucial role in the progression of renal fibrosis, particularly in chronic active renal allograft rejection (CAR). This study explored the mechanisms by which METTL3 promotes renal allograft fibrosis, focusing on its role in the macrophage-to-myofibroblast transition (MMT). Using a comprehensive experimental approach, including TGF-β1-induced MMT cell models, METTL3 conditional knockout (METTL3 KO) mice, and renal biopsy samples from patients with CAR, the study investigates the involvement of METTL3/Smad3 axis in driving MMT and renal fibrosis during the episodes of CAR.
View Article and Find Full Text PDFIr J Med Sci
January 2025
Faculty of Medicine, Department of Pediatric Surgery Division of Pediatric Urology, Eskisehir Osmangazi University, Eskişehir, Turkey.
Background: Hydronephrosis developing at the ureteropelvic junction due to obstruction poses clinical challenges as it has the potential to cause renal damage.
Aims: This study aims to evaluate how well machine learning models such, as XGBClassifier and Logistic Regression can be used to predict the need for treatment in patients, with hydronephrosis resulting from ureteropelvic junction obstruction.
Methods: Hydronephrosis was diagnosed in the medical records of patients from January 2015 to December 2020.
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