Malignant Peripheral Nerve Sheath Tumour: CT and MRI Findings.

Case Rep Radiol

Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford, 81-00133 Rome, Italy.

Published: August 2013

AI Article Synopsis

  • Malignant peripheral nerve sheath tumor (MPNST) is a rare cancer that typically occurs more often in individuals with Neurofibromatosis type 1 (NF1), but five cases have been documented in patients without NF1 arising from the parapharyngeal space (PPS).
  • Imaging techniques, specifically CT scans and MRIs, were utilized in a reported case of MPNST in the PPS of a patient who lacked any family history or symptoms of NF1.
  • The imaging results were analyzed and correlated with the histopathological diagnosis to inform proper treatment planning.

Article Abstract

Malignant peripheral nerve sheath tumour (MPNST) is extremely rare malignancy in the general population, occurring more frequently in patients with Neurofibromatosis type 1 (NF1). In the literature five cases of MPNST arising from the parapharyngeal space (PPS) in patients without neurofibromatosis have been reported. We report imaging techniques in a patient with MPNST in the PPS, who had neither a family history nor sign of NF1. Computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed for a correct therapeutic planning. CT and MRI findings were correlated with hystopathological diagnosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732584PMC
http://dx.doi.org/10.1155/2013/517879DOI Listing

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