We are grateful to the commentators for taking the time to respond to our article. Too many interesting and important points have been raised for us to tackle them all in this response, and so in the below we have sought to draw out the major themes. These include problems with both the term 'ultimate causation' and the proximate-ultimate causation dichotomy more generally, clarification of the meaning of reciprocal causation, discussion of issues related to the nature of development and phenotypic plasticity and their roles in evolution, and consideration of the need for an extended evolutionary synthesis.
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http://dx.doi.org/10.1007/s10539-013-9380-4 | DOI Listing |
J Med Genet
January 2025
Department of Gastroenterology, Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), Institut Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
J Integr Plant Biol
January 2025
Plant Stress Physiology and Proteomics Laboratory, College of General Education, Kookmin University, Seoul, 02707, South Korea.
This commentary discusses the recent identification of hydrogen peroxide as systemic acquired resistance-inducing signal and its dose-dependent effect on salicylic acid biosynthesis in the systemic tissues in response to a pathogen attack.
View Article and Find Full Text PDFClin Transl Med
January 2025
Earle A. Chiles Research Institute, Providence Cancer Center, Portland, Oregon, USA.
Child Dev
January 2025
Gangneung-Wonju National University, Gangneung, Republic of Korea.
This response to a Commentary by Delgado-Ron, Jeyabalan, Watt, and Salway (2024) on Cimpian, Timmer, and Kim's (2023) paper discusses and clarifies some key issues in applying the new data-validity sensitivity analysis proposed by Cimpian et al. (2023). The differences in the applications of the method by Delgado-Ron et al.
View Article and Find Full Text PDFChildren (Basel)
November 2024
Section of Rheumatology, Department of Paediatrics, Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, 28 Oki Drive NW, Calgary, AB T3B 6A8, Canada.
Juvenile idiopathic arthritis (JIA) is a chronic autoimmune condition in children that often requires long-term pain management, which can include opioid use. In the context of Canada's ongoing overdose crisis, youth with JIA face risks due to potential opioid dependency and exposure to toxic drug supplies. This commentary proposes an integrated approach combining chronic disease management with harm reduction strategies specifically tailored for JIA patients.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!