Morphological and immunological data on the efficiency of the conservative treatment of hypertrophic tonsils in 59 children are presented. Biopsies of tonsils were examined before and after treatment. Tonsils reduced in size as a result of treatment, their changes indicated activation of the morphological manifestations of cellular and humoral immunity. Intramuscular treatment with thymalin resulted in normalization of the peripheral blood immunological indexes. The lacuna lavage with thymalin led to the normalization of the disturbed epithelial barrier structure.
Download full-text PDF |
Source |
---|
Genes Chromosomes Cancer
January 2025
Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
Mature aggressive B-cell lymphomas, such as Burkitt lymphoma (BL) and Diffuse large B-cell lymphoma (DLBCL), show variations in microRNA (miRNA) expression. The entity of High-grade B-cell lymphoma with 11q aberration (HGBCL-11q) shares several biological features with both BL and DLBCL but data on its miRNA expression profile are yet scarce. Hence, this study aims to analyze the potential differences in miRNA expression of HGBCL-11q compared to BL and DLBCL.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
January 2025
Department of Otolaryngology Head and Neck Surgery, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, China.
Objective: This study aims to explore the clinical effects of simultaneous balloon eustachian tuboplasty (BET) in treating chronic secretory otitis media (COME) in children with bilateral tonsil and adenoid hypertrophy (TAH), providing a theoretical basis for the clinical application of BET.
Methods: From January 2023 to January 2024, 30 children diagnosed with COME and bilateral TAH were included in this retrospective study at our hospital. The cohort comprised a total of 55 affected ears.
J Pediatr Endocrinol Metab
January 2025
Division of Pediatric Neurology, Department of Pediatrics and Child Health, Erciyes University, Faculty of Medicine, Kayseri, Türkiye.
Objectives: Tangier disease (TD) is a rare autosomal recessive condition characterized by high-density lipoprotein (HDL) deficiency; involving symptoms of polyneuropathy, hyperplastic orange-yellow tonsils, vision disorder, and sudden cardiac death. The major clinical symptoms of TD may not all be co-present. This study evaluates patients diagnosed with TD in childhood to improve the possibility of early diagnosis of asymptomatic cases by reporting our patients' clinical characteristics in order to minimize delayed diagnosis and emphasize the importance of TD, easily detected by HDL measurement.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
January 2025
Department of General Surgery, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Objective: The hypothesis tested was the negative impact of electronic smoke exposure on the developing of respiratory infection, specifically in the upper tract. In this study, we aimed to investigate if smoke exposure increased the number of tonsillectomy surgery in children compared to the hernia repair control group.
Methods: The design of our study was retrospective case-control.
Turk Arch Otorhinolaryngol
January 2025
Private Clinic, Department of Otorhinolaryngology-Head and Neck Surgery, Ankara, Türkiye.
Objective: To investigate the association between clinical factors and post-tonsillectomy hemorrhage (PTH) including rebleeding episodes.
Methods: The medical records of 1,082 patients who underwent tonsillectomy between May 2018 and April 2019 were reviewed. The entire study cohort included 431 (39.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!