In the midst of frequent reports about "the asthma epidemic," results from a number of studies by the manitoba centre for health policy have shown stable or decreasing prevalence of an overall indicator of respiratory diseases which includes asthma. To resolve these apparently contrary findings, we conducted a time trend analysis using administrative data. results revealed significant potential for diagnostic exchange: asthma prevalence increased, but that of bronchitis decreased.
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Sensors (Basel)
December 2024
Institute of Autmatic Control, University of Kaiserslautern-Landau, 67653 Kaiserslautern, Germany.
Harsh operating conditions imposed by vehicular applications significantly limit the utilization of proton exchange membrane fuel cells (PEMFCs) in electric propulsion systems. Improper/poor management and supervision of rapidly varying current demands can lead to undesired electrochemical reactions and critical cell failures. Among other failures, flooding and catalytic degradation are failure mechanisms that directly impact the composition of the membrane electrode assembly and can cause irreversible cell performance deterioration.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Nobel Eye Institute, Taipei 10041, Taiwan.
: To evaluate the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) surgery and refractive lens exchange (RLE) surgery in moderate to high myopia patients. : A retrospective cohort study was performed, and patients receiving KLEx or RLE surgeries with myopia within -3.00 to -10.
View Article and Find Full Text PDFActa Biomater
January 2025
Institute of Smart Biomedical Materials, School of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, PR China. Electronic address:
The U.S. Food and Drug Administration (FDA) has issued a boxed warning and mandated additional safety measures for all gadolinium-based contrast agents (GBCAs) used in clinical magnetic resonance imaging (MRI) due to their prolonged retention in the body and associated adverse health effects.
View Article and Find Full Text PDFAm J Ther
January 2025
Northwell, New Hyde Park, NY, Department of Medicine, Manhasset, NY.
Background: C3 glomerulopathy (C3G) is a rare disease affecting the complement alternative pathway, categorized into dense deposit disease and C3 glomerulonephritis. Dense deposit disease predominantly affects younger individuals, while C3 glomerulonephritis tends to manifest in older populations. The diseases are characterized by dysregulation of the complement alternative pathway, leading to the deposition of complement components in the glomeruli and subsequent renal dysfunction.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Division of Neonatology, Department of Pediatrics, Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, the Netherlands.
Importance: Preventive efforts in pregnancy-related alloimmunization have considerably decreased the prevalence of hemolytic disease of the fetus and newborn (HDFN). International studies are therefore essential to obtain a deeper understanding of the postnatal management and outcomes of HDFN. Taken together with numerous treatment options, large practice variations among centers may exist.
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