AI Article Synopsis

  • A study investigated the impact of Helicobacter pylori eradication therapy on blood sugar control in Japanese patients with type 2 diabetes.
  • The research involved 72 subjects, and tested their blood glycosylated hemoglobin (A1C) levels before and after the treatment.
  • Results indicated no significant changes in A1C levels, suggesting that H. pylori eradication does not notably influence glycemic control in these patients.

Article Abstract

Since infection with Helicobacter pylori has been suggested to play a pathogenic role in diabetes mellitus, we investigated whether eradication therapy for H. pylori might affect glycemic control in Japanese subjects with type 2 diabetes. A total of 72 subjects (55 males, 17 females; aged 63.7 years) with type 2 diabetes who received eradication therapy for H. pylori were included. The change of their blood glycosylated hemoglobin (A1C) levels 3 months before (-3 m) the H. pylori eradication, as well as 3 months (3 m) and 6 months (6 m) after were evaluated. Their A1C levels did not show any significant change after therapy {6.9 [0.1]% (-3 m) to 7.0 [0.1]% (3 m); P = 0.3, 7.0 [0.1] (6 m); P = 0.3}. Our findings suggest that the eradication therapy for H. pylori does not, at least profoundly, affect glycemic control in Japanese subjects with type 2 diabetes.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742360PMC
http://dx.doi.org/10.4137/JCM.S10828DOI Listing

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