The performance of a real-time PCR assay targeting the Tropheryma whipplei rpoB gene was evaluated using test strains and 1,236 clinical specimens in a national reference laboratory. The novel rpoB-PCR assay proved to be specific, revealed improved analytical sensitivity, and substantially accelerated detection of T. whipplei DNA in clinical specimens.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889782 | PMC |
| http://dx.doi.org/10.1128/JCM.01703-13 | DOI Listing |
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