AI Article Synopsis
- Periodontitis is an inflammatory disease that impacts the structures supporting teeth, starting with bacterial biofilms at the gum line.
- The composition of these biofilms in periodontitis has been thoroughly studied, but the influence of the host's environmental responses on biofilm formation is still unclear.
- This review focuses on how factors like pH, temperature, cytokines, hormones, and oxidative stress affect the development of periodontal biofilms and the virulence of bacteria involved.
Article Abstract
Periodontitis is a common inflammatory disease affecting the tooth-supporting structures. It is initiated by bacteria growing as a biofilm at the gingival margin, and communication of the biofilms differs in health and disease. The bacterial composition of periodontitis-associated biofilms has been well documented and is under continual investigation. However, the roles of several host response and inflammation driven environmental stimuli on biofilm formation is not well understood. This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759961 | PMC |
| http://dx.doi.org/10.3390/ijms140817221 | DOI Listing |
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