Percutaneous absorption is affected by numerous factors. Whether they are internal or external factors, the compounding pharmacist must collectively consider these variables in order to provide a safe and effective topical preparation for the patient. By considering the physiochemical and dermal factors that affect percutaneous absorption of a medication, an effective topical medication can be formulated to treat the patient's specific indication. Furthermore, this article will review the background information necessary to formulate transdermal prescriptions for their patients.
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