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Psychotropic Polypharmacy in Dementia: A Retrospective Analysis for People with Neuropsychiatric Symptoms Referred to an Australian Dementia Support Service.
Drugs Aging
January 2025
The Dementia Centre, HammondCare, St Leonards, NSW, Australia.
Background And Objectives: Despite their limited benefits and serious adverse effects, psychotropics remain frequently prescribed for neuropsychiatric symptoms (NPS) of dementia. Psychotropic polypharmacy, the use of two or more concomitant psychotropic medications, is therefore not recommended for people with dementia. The objectives of this study were to investigate the prevalence of psychotropic polypharmacy in Australians living with dementia whose caregivers sought external NPS support from Dementia Support Australia (DSA; the national provider of NPS support) and the association of psychotropic polypharmacy with their demographics and NPS characteristics.
View Article and Find Full Text PDFThere is no "I" in team: Implications for academic radiology.
Clin Imaging
January 2025
The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
All of us must find the right balance between team science and fostering leadership with dynamic colleagues. That dichotomy was well-encapsulated in a famous exchange between basketball players Shaquille O'Neal and Kobe Bryant regarding there "being no 'I' in team". In our view, there is nothing more satisfying than collaborating with a team of people and publishing impactful papers or making key discoveries.
View Article and Find Full Text PDFAI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus.
Heliyon
January 2025
Center for Global Health Research, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602 105, Tamil Nadu, India.
AI-optimized electrochemical aptasensors are transforming diagnostic testing by offering high sensitivity, selectivity, and rapid response times. Leveraging data-driven AI techniques, these sensors provide a non-invasive, cost-effective alternative to traditional methods, with applications in detecting molecular biomarkers for neurodegenerative diseases, cancer, and coronavirus. The performance metrics outlined in the comparative table illustrate the significant advancements enabled by AI integration.
View Article and Find Full Text PDFSocial vulnerability index associated with higher COVID-19 seroprevalence in Nigeria.
Glob Health Action
December 2024
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Social vulnerability has been shown to be a strong predictor of disparities in health outcomes. A common approach to estimating social vulnerability is using a composite index, such as the social vulnerability index (SVI), which combines multiple factors corresponding to key social determinants of health. Lawal and Osayomi created an SVI to explore key social determinants of health-related COVID-19 infection among the Nigerian population.
View Article and Find Full Text PDFA comparison of health-related quality of life between continuous ambulatory peritoneal dialysis and automated peritoneal dialysis in children with stage 5 chronic kidney disease in Thailand: a randomized controlled trial.
Pediatr Nephrol
January 2025
Division of Nephrology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Background: Improving health-related quality of life (HRQoL) is one of the main goals in managing stage 5 chronic kidney disease (CKD). However, limited evidence compares HRQoL between continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) in children. This open-label randomized controlled trial (RCT) aimed to compare HRQoL in pediatric patients with stage 5 CKD receiving CAPD vs.
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