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A woman in her 70s with well-controlled HIV on antiretroviral therapy presented with a several-month history of an asymptomatic perianal lesion. Skin examination showed a 0.5-1 cm red-pink, shiny, exophytic papule with visible telangiectasias near the anal verge.

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Purpose: This systematic review aims to consolidate evidence on ophthalmological manifestations of angiolymphoid hyperplasia with eosinophilia, focusing on its presentation, diagnosis, and management.

Methods: Preferred reporting items for systematic reviews and meta-analyses-adherent systematic review was conducted across 3 databases from inception until September 2024. Case reports and series detailing angiolymphoid hyperplasia with eosinophilia in ocular structures were included.

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Characteristics of F-FDG PET/CT in patients with Kimura's disease from China.

BMC Med Imaging

October 2024

Department of Nuclear Medicine, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, China.

Article Synopsis
  • Kimura's disease (KD) is a rare inflammatory condition that is challenging to diagnose due to its vague symptoms and imaging characteristics, prompting a study to evaluate the effectiveness of F-FDG PET/CT in identifying it.
  • The study analyzed clinical and imaging data from 8 patients confirmed to have KD, revealing common features such as high F-FDG uptake in lesions, regional or generalized lymphadenopathy, and concurrent subcutaneous masses and salivary gland involvement in some cases.
  • Findings suggest that KD should be suspected when patients present with specific imaging patterns on F-FDG PET/CT, particularly when eosinophilia is present, indicating that better awareness and diagnostic tools are needed for this condition.
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Article Synopsis
  • Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign tumor that was diagnosed in a 25-year-old female patient with distinctive skin lesions on her scalp.
  • A biopsy confirmed the diagnosis of ALHE and revealed an infestation of Demodex mites in her sebaceous glands.
  • The patient's condition improved significantly after 7 weeks of treatment involving cryotherapy and the topical use of metronidazole gel, suggesting that Demodex mites might play a role in triggering ALHE.
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Kimura disease: A rare case in Vietnamese woman.

Asia Pac Allergy

August 2024

Department of Physiology, Pathophysiology & Immunology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Article Synopsis
  • Kimura disease (KD) is a rare, benign inflammatory condition mainly seen in Asian males, marked by tissue masses, swollen lymph nodes, and elevated eosinophil and IgE levels.
  • A unique case of KD was reported in a 31-year-old Vietnamese woman with facial masses and long-standing itching, with biopsy results confirming the diagnosis.
  • The findings suggest that KD can occur in females and emphasize the importance of histopathological examinations for accurate diagnosis, highlighting the need for increased awareness of this condition among Asian women.
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