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Giant Basal Cell Carcinoma Within a Marjolin's Ulcer: A Case Discussion.
Cureus
August 2024
Surgical Oncology, University of Miami, Miami, USA.
Marjolin's ulcers are cutaneous malignancies that arise from chronic wounds, often secondary to burns. While squamous cell carcinoma is the most prevalent type, rare instances of other tumors, such as basal cell carcinoma, have occurred. These tumors are challenging to treat due to their high recurrence rate and aggressive behavior.
View Article and Find Full Text PDFClinical Characteristics and Treatment of Marjolin's Ulcer at a Major Burn Center in Northwest China: A Retrospective Review of 126 Cases.
J Burn Care Res
January 2025
Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.
Marjolin's ulcer (MU) is a rare, aggressive skin tumor. There are numerous case reports but large long-term studies are lacking, necessitating further exploration of its treatment. This study aimed to summarize and analyze the characteristics, treatment methods, and prognosis of MU.
View Article and Find Full Text PDFManagement Dilemma in a Large Fungating Squamous Cell Carcinoma Over a Marjolin's Ulcer on the Chest Wall Coexisting With Severe Post-Burn Contracture of the Neck.
Cureus
July 2023
General Surgery, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Marjolin's ulcer is a premalignant condition occurring over scars and chronically inflamed tissue. Squamous cell carcinoma is the most common malignancy associated with Marjolin's ulcer. The progression of disease and metastasis is relatively slow due to scarring and meagre lymphatic and vascular supply over these scars.
View Article and Find Full Text PDFA case report: Management dilemma in a large fungating squamous cell carcinoma over a Marjolin's ulcer on the chest wall coexisting with severe post burn contracture of the neck.
Int J Surg Case Rep
September 2023
Department of Surgical Oncology, All India Institute of Medical Sciences Bhopal, M.P., India. Electronic address:
Introduction And Importance: Marjolin's ulcer is a premalignant condition occurring over scars and chronically inflamed tissue. Squamous cell carcinoma is the most common malignancy associated with Marjolin's ulcer. These are rare tumors which spread locally and once infiltrating, may lead to distant spread.
View Article and Find Full Text PDFWhen Benign Becomes Cancer: Malignant Degeneration of Chronic Inflammation.
Semin Plast Surg
August 2021
Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Chronic inflammation, long implicated in the genesis of malignancy, is now understood to underlie an estimated 25% of all cancers. The most pertinent malignancies, to the plastic surgeon, associated with the degeneration of chronic inflammation include Marjolin's ulcer, breast implant-associated large cell lymphoma, radiation-induced sarcoma, and Kaposi's sarcoma. The cellular and genetic damage incurred by a prolonged inflammatory reaction is controlled by an increasingly understood cytokinetic system.
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