Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744243 | PMC |
| http://dx.doi.org/10.4172/2155-9872.1000e112 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis, Physicochemical Properties, and Ion Recognition Ability of Azulene-Based Bis-(Thio)Semicarbazone.
Molecules
December 2024
"C. D. Nenitzescu" Institute of Organic and Supramolecular Chemistry, Splaiul Independentei 202B, 060023 Bucharest, Romania.
Azulene-1,3-bis(semicarbazone), , and azulene-1,3-bis(thiosemicarbazone), , were synthesized by the acid-catalyzed condensation reactions of semicarbazide and thiosemicarbazide, respectively, with azulene-1,3-dicarboxaldehyde in stoichiometric amounts. Compounds and were identified by high-resolution mass spectrometry and characterized by IR, H-NMR, C-NMR, and UV-vis spectroscopic techniques. Crystal structure determination of azulene-1,3-bis(thiosemicarbazone) shows that the thiosemicarbazone units exhibit a -closed conformation, with both arms oriented in the same direction and adopting an configuration with respect to the imine linkages.
View Article and Find Full Text PDFIn-cell NMR reveals metabolic adaptations in central carbon pathways driving antibiotic tolerance in Typhimurium.
Anal Methods
January 2025
Department of Health Technology, Technical University of Denmark, 2800 Kgs, Lyngby, Denmark.
Antibiotic tolerance presents a significant challenge in eradicating bacterial infections, as tolerant strains can survive antibiotic treatment, contributing to the recurrence of infections and the development of resistance. However, unlike antibiotic resistance, tolerance is not detectable by standard susceptibility assays such as minimal inhibitory concentration (MIC) tests. Consequently, antibiotic tolerance often goes unnoticed in clinical settings.
View Article and Find Full Text PDFA Simple and Rapid "Turn-On" Fluorescent Probe Based on Binuclear Schiff Base for Zn and Its Application in Cell Imaging and Test Strips.
Molecules
December 2024
High & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
A series of colorful binuclear Schiff bases derived from the different diamine bridges including 1,2- ethylenediamine (bis-Et-SA, bis-Et-4-NEt, bis-Et-5-NO, bis-Et-Naph), 1,2-phenylenediamine (bis-Ph-SA, bis-Ph-4-NEt, bis-Ph-5-NO, bis-Ph-Naph), dicyano-1,2-ethenediamine (bis-CN-SA, bis-CN-4-NEt, bis-CN-5-NO, bis-CN-Naph) have been designed and prepared. The optical properties of these binuclear Schiff base ligands were fully determined by UV-Vis absorption spectroscopy, fluorescence emission spectroscopy, and time-dependent-density functional theory (TD-DFT) calculations. The inclusion of D-A systems and/or π-extended systems in these binuclear Schiff base ligands not only enables adjustable RGB light absorption and emission spectra (300~700 nm) but also yields high fluorescence quantum efficiencies of up to 0.
View Article and Find Full Text PDFGallic acid-guar gum and chitosan-based polyelectrolyte complex film exhibited enhanced wound healing in full-thickness excision wound model.
J Biomater Sci Polym Ed
January 2025
Department of Medical Affairs, Curie Sciences, Samastipur, Bihar, India.
Article Synopsis
- Recent developments in wound dressings focus on natural bioactives like guar gum (GG) and gallic acid (GA), which can enhance healing compared to traditional materials.
- The study created a GA-GG conjugate through a polymerization process, confirming its successful integration and beneficial structural changes via various spectroscopic analyses.
- A polyelectrolyte complex (PEC) film made with chitosan showed strong antioxidant and antimicrobial properties, high swelling rates, and excellent wound healing efficacy, achieving 94.5% closure in comparison to untreated controls.
Five racemic phthalides from the aerial parts of Lycopodiastrum casuarinoides and their neuroprotective activities.
Phytochemistry
January 2025
Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, 410013, China. Electronic address:
Five racemic phthalides (1-5), including four undescribed phthalides monomers [(+)-1, (+)-2, (-)-2 and (-)-3], four undescribed phthalide dimers [(+)-4, (-)-4, (+)-5 and (-)-5], together with two known compounds [(-)-1 and (+)-3], were isolated from the aerial parts of Lycopodistrum casuarinoides. Their chemical structures were delineated by extensive spectroscopic data (UV, 1D/2D NMR, HRESIMS), in combination with the comparison of the experimental and calculated electronic circular dichroism spectra, calculated spin-spin coupling constants, and calculated NMR. All compounds were reported from Lycopodiaceae family for the first time.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!