Background: Intravascular lymphoma is a rare and fatal disease that can have central nervous system (CNS) manifestations. It is usually a diagnosis made postmortem. This is partly due to its varied presentation, which lends itself to the complexity of diagnosis.
Case Description: We report a rare case of intravascular lymphoma in the brain found antemortem.
Conclusion: Review of the literature shows that a timely diagnostic tissue biopsy together with aggressive combination chemotherapy treatment can improve patient outcome.
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http://dx.doi.org/10.4103/2152-7806.115709 | DOI Listing |
JACC Case Rep
December 2024
Department of Cardiology, Centro Hospitalar Universitário Lisboa Norte,Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal.
An 80-year-old woman with a history of B-cell non-Hodgkin lymphoma presented to the emergency department with exertional dyspnea and lower limb edema. A transthoracic echocardiogram revealed a large extracardiac mass invading the right atrium. A diagnostic transcatheter endomyocardial biopsy guided by intracardiac echocardiography was performed.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Saitama Citizens Medical Center, Saitama, JPN.
Intravascular large B-cell lymphoma (IVLBCL) is characterized by clinical presentations described as B symptoms, consisting of fever, night sweats, and weight loss. Intravascular lymphomas are more frequently diagnosed in elderly patients and are challenging to diagnose because of their nonspecific clinical presentation. Malignant lymphomas are recognized as the leading cause of fever of unknown origin.
View Article and Find Full Text PDFMalays J Pathol
December 2024
Universiti Kebangsaan Malaysia, Faculty of Medicine, Department of Pathology, Kuala Lumpur, Malaysia.
No abstract available.
View Article and Find Full Text PDFJ Clin Exp Hematop
December 2024
Department of Pathology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Intravascular accumulation of atypical large lymphoid cells is a rare condition that necessitates a differential diagnosis of intravascular lymphoma (IVL). Recently, a non-neoplastic condition known as benign atypical intravascular CD30+ T-cell proliferation (BAITP) has been identified. This condition is characterized by CD30+ and CD3+ or CD4+ atypical T-cells and is often associated with trauma and chronic inflammation.
View Article and Find Full Text PDFIntern Med
December 2024
Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Japan.
Objective Intravascular large B-cell lymphoma (IVLBCL) is a critical cause of fever of unknown origin (FUO). While a pathological analysis is essential for diagnosing IVLBCL, the indications for an invasive procedure may be ascertained using easy, non-invasive tests. The lymphocyte-to-monocyte ratio (LMR) can reportedly predict the diagnosis of malignant lymphoma in patients with lymphadenopathy; however, its clinical utility in predicting an IVLBCL diagnosis in patients with FUO remains to be elucidated.
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