Toxocara canis and Toxocara cati are common helminths that reside in the intestinal tract of cats and dogs. Toxocariasis and, commonly, T. canis, is a disease commonly seen in children, which is characterised by hypereosinophilia, hepatomegaly, fever, transient pulmonary infiltration, and hypergammaglobulinaemia. Humans, who are not the actual host for these parasitic worms, are infected following oral intake of the infective eggs. Radiological differentiation of hepatic toxocariasis can be difficult, as liver lesions, which present as multiple hypoechoic lesions with regular borders, can look like a tumour, an infarction or an infection. We report on a case that presented to our emergency department (ED) with abdominal pain. During the initial review, the pathology in the liver was thought to be an infarction or an infection; however, the patient was diagnosed with hepatic toxocariasis following further evaluation.

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http://dx.doi.org/10.5152/tpd.2013.33DOI Listing

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Article Synopsis
  • Toxocariasis is a zoonotic infection from dog and cat larvae that can pose serious health risks to humans, with a case described involving a 21-year-old male who had close contact with a pet dog.
  • The patient's symptoms initially resembled a common liver abscess, with lab results showing elevated white blood cells and IgE levels, but persistent fever led to more testing revealing a Toxocara-induced liver abscess.
  • Successful treatment with albendazole demonstrated significant improvement, highlighting the importance of considering toxocariasis in liver abscess cases, especially in regions with high rates of infection, and the need for thorough diagnostic methods beyond serological tests.
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Article Synopsis
  • The condition can lead to visceral and ocular larva migrans, with rare cases involving the central nervous system (neurotoxocariasis), potentially causing serious issues like meningitis or seizures.
  • There is concern about the underdiagnosis of neurotoxocariasis due to its vague symptoms, and while a link to aneurysms hasn't been proven, it's suggested as an area for future research.
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Toxocariasis is a zoonosis that represents a serious threat to public health particularly in tropical and subtropical areas. Currently, albendazole, the most effective drug for treating visceral toxocariasis, shows moderate efficacy against the larvae in tissues and has some adverse effects. Artemether is an antiparasitic drug mainly used in the treatment of malaria and showed effectiveness against numerous helminthic infections.

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There are currently insufficient anthelmintic medications available for the treatment of toxocariasis. For instance, Albendazole (ABZ) is the preferred medication, but its effectiveness against tissue-dwelling parasites is limited. In addition, Metformin (MTF) is a widely used oral antidiabetic medication that is considered to be safe for treatment.

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