First clinical manifestation of Brugada syndrome during pregnancy.

Herzschrittmacherther Elektrophysiol

Department of Internal Medicine I, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany.

Published: September 2013

AI Article Synopsis

  • The impact of hormonal changes during pregnancy on Brugada syndrome is still not well understood.
  • Only a few case reports exist that detail occurrences of Brugada syndrome in pregnant patients.
  • A case study is presented where a woman first showed signs of Brugada syndrome during pregnancy, but a definitive diagnosis was only made after childbirth through a drug challenge test with ajmaline.

Article Abstract

The role of hormonal changes during pregnancy in Brugada syndrome is unknown. Only rare case reports of Brugada syndrome during pregnancy have been published. In this article, we describe a patient with first clinical manifestation of Brugada syndrome during pregnancy. The definitive diagnosis could only be achieved by drug challenge with ajmaline after childbirth because the spontaneous typical Brugada-like pattern was absent. Elevated hormone levels during pregnancy may increase the risk for arrhythmias in particular cases.

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Source
http://dx.doi.org/10.1007/s00399-013-0287-1DOI Listing

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