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Kaposi sarcoma (KS) is a soft tissue tumor primarily occurring in immunosuppressed patients and, although it has been described, dissemination of KS is rare. This case involves a patient with acquired immunodeficiency syndrome (AIDS) and biopsy-proven cutaneous KS presenting with hematemesis suspected due to gastrointestinal involvement in whom endoscopy with biopsy was contraindicated due to dual antiplatelet therapy (DAPT) and the hypervascular nature of KS tumors. Alternatively, the diagnosis was made via macroscopic findings on bronchoscopy, which demonstrated neovascular lesions, confirming visceral KS.

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Gastric adenocarcinoma with intestinal progenitor cell differentiation: a morphologically underdiagnosed and more invasive distinctive type of gastric adenocarcinoma.

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Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Pathology and Institute of Molecular Pathology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University Nanchang 330006, Jiangxi, China.

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Peptic ulcer disease (PUD) is a common gastrointestinal diagnosis affecting the stomach and proximal duodenum. A contained perforation with pancreatic communication is an exceedingly rare subtype where gastroduodenal perforation is limited by the surrounding pancreas, preventing free leakage of gastric and pancreatic contents into the peritoneal cavity. A 48-year-old male with a history of perforated antral ulcer requiring surgical management and placement of a Graham patch presented with upper gastrointestinal bleeding.

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