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The Accreditation Council for Graduate Medical Education (ACGME) plays a pivotal role in ensuring the quality of graduate medical education (GME) training across the United States. Central to the success of this mission are designated institutional officials (DIOs), who usually serve as chief GME officers within the ACGME-accredited sponsoring institutions (SIs). Despite the critical role of DIOs, the qualifications, level of administrative support, and responsibilities of DIOs are not defined and vary significantly among SIs.
View Article and Find Full Text PDFCTGCT, Centre of Excellence for the Technologies of Gene and Cell Therapy: Collaborative translation of scientific discoveries into advanced treatments for neurological rare genetic diseases and cancer.
Comput Struct Biotechnol J
December 2024
Centre for the Technologies of Gene and Cell Therapy, National Institute of Chemistry, Hajdrihova 19, SI1000 Ljubljana, Slovenia.
The emerging field of precision medicine relies on scientific breakthroughs to understand disease mechanisms and develop cutting-edge technologies to overcome underlying genetic and functional aberrations. The establishment of the Centre of Excellence for the Technologies of Gene and Cell Therapy (CTGCT) at the National Institute of Chemistry (NIC) in Ljubljana represents a significant step forward, as it is the first centre of its kind in Slovenia. The CTGCT is poised to spearhead advances in cancer immunotherapy and personalised therapies for neurological and other rare genetic diseases.
View Article and Find Full Text PDFMedicine as a Mission: Ida Sophia Scudder's Contributions to Indian Healthcare.
Cureus
December 2024
Community Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.
This review article examines the life and medical contributions of Dr. Ida Sophia Scudder (1870-1960), a pioneering American physician and missionary who significantly impacted healthcare in India. Born into a family of medical missionaries, Scudder initially resisted following in her family's footsteps.
View Article and Find Full Text PDFDefining and Measuring Crewmember Operational State for Spaceflight Operations.
Aerosp Med Hum Perform
December 2024
Introduction: A suite of human health and performance metrics can be used to provide a holistic cognitive, physical, and emotional view of an individual and assess how well they are integrated with the overall system during spaceflight missions. The combination of such individual metrics as defined here is notionally termed "crewmember operational state."
Methods: This work identifies and defines the contributing components that comprise the proposed crewmember operational state.
1,2-DCA biodegradation potential of an aquifer assessed in situ and in aerobic and anaerobic microcosms.
Environ Microbiome
December 2024
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo, Palermo, Italy.
Background: 1,2-dichloroethane (1,2-DCA) biodegradation can occur through aerobic or anaerobic pathways that can be exploited in bioremediation strategies. Bioremediation interventions are site specific and generally based on anaerobic pathways, nevertheless expanding knowledge on proper conditions favoring the biodegradation and especially on 1,2-DCA degrading microorganisms is crucial. In this work the intrinsic biodegradation potential of an aquifer impacted by Chlorinated Aliphatic Hydrocarbons (mainly 1,2-DCA) was evaluated by characterizing the aquifer microbiome across space and time and by setting up biostimulation treatments in microcosms under different aerobic and anaerobic conditions, in parallel.
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