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| http://dx.doi.org/10.1177/014107689008300726 | DOI Listing |
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[Access requirements for medically assisted death: an open question.].
Recenti Prog Med
January 2025
Dipartimento di Biomedicina, neuroscienze e diagnostica avanzata, Università di Palermo.
The commentary focuses on the requirements for access to medical assistance in dying in countries where this practice is legal. It shows that the different solutions adopted reflect a different balance between the principles of protection of life, reduction of suffering and respect for autonomy. The article also analyses the potential ethical problems associated with the decision-making capacity of psychiatric patients.
View Article and Find Full Text PDFAssessing the Fear of Covid-19 in Psychiatric Patients: Results from an Italian Multicentric Study.
Clin Neuropsychiatry
December 2024
IRCSS San Gerardo, Monza, Italy.
Objective: Even though the COVID-19 emergency has concluded, its consequences are still relevant. Recent evidence suggests that a significant proportion of individuals experience persistent symptoms long after the initial infection has resolved, classified as "Long COVID" condition. Fear of COVID-19 increases anxiety and stress levels in healthy individuals and exacerbates the symptoms of those with pre-existing psychiatric disorders; therefore understanding the impact of the pandemic on psychiatric disorders remains of utmost importance.
View Article and Find Full Text PDFAltered Pain Perception and Nociceptive Thresholds in Major Depression and Anxiety Disorders: A Meta-Analysis.
Neurosci Biobehav Rev
January 2025
Department of Psychiatry, University of Toronto, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada; Cundill Centre for Child and Youth Depression, Toronto, ON, Canada.
Psychiatric conditions can affect the experience of pain. Several reports indicate that Major Depressive Disorder (MDD) is associated with an increased pain threshold, while Anxiety Disorders (ADs) may amplify the perception of pain. However, available data on the nociceptive threshold in these psychiatric conditions are controversial.
View Article and Find Full Text PDFHikikomori (prolonged social withdrawal) and co-occurring psychiatric disorders and symptoms in adolescents and young adults: A scoping review.
Compr Psychiatry
January 2025
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Electronic address:
Background: Hikikomori, or prolonged social withdrawal, is a clinical condition usually emerging during adolescence or young adulthood, characterized by severe self-isolation in one's home, and often associated with other psychiatric disorders and symptoms.
Objective: The study summarized evidence of hikikomori diagnostic criteria, clinical manifestations, and comorbidity with psychiatric disorders and symptoms in adolescents and young adults.
Methods: A scoping review was conducted following PRISMA guidelines, with four electronic databases searched for original works in English, French, and Italian published since 2010.
Conformational Antibodies to Proteolipid Protein-1 and Its Peripheral Isoform DM20 in Patients With CNS Autoimmune Demyelinating Disorders.
Neurol Neuroimmunol Neuroinflamm
March 2025
Neuroimmunology Laboratory and Neuroimmunology Research Section, IRCCS Mondino Foundation, Pavia, Italy.
Background And Objectives: Antibodies to proteolipid protein-1 (PLP1-IgG), a major central myelin protein also expressed in the peripheral nervous system (PNS) as the isoform DM20, have been previously identified mostly in patients with multiple sclerosis (MS), with unclear clinical implications. However, most studies relied on nonconformational immunoassays and included few patients with non-MS CNS autoimmune demyelinating disorders (ADDs). We aimed to investigate conformational PLP1-IgG in the whole ADD spectrum.
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