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Evaluating Vonoprazan for the treatment of erosive GERD and heartburn associated with GERD in adults.
Expert Opin Pharmacother
December 2024
Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Article Synopsis
- Gastroesophageal reflux disease (GERD) is a chronic condition divided into two types: erosive reflux disease (ERD) and non-erosive reflux disease (NERD), primarily influenced by acid secretion and managed with various acid-suppressant medications.
- Since the 1970s, treatments have evolved from histamine-H-receptor antagonists to proton pump inhibitors (PPIs), and recently, potassium-competitive acid blockers (p-CABs) like Vonoprazan have emerged, offering improved efficacy and safety.
- Vonoprazan has demonstrated effectiveness in managing ERD and related symptoms, showing potential advantages over older PPIs, with ongoing research expected to explore its long-term benefits in treating other acid-related
[Chinese expert consensus on the etiological diagnosis of adult bronchiectasis].
Zhonghua Jie He He Hu Xi Za Zhi
October 2024
Bronchiectasis is a highly heterogeneous chronic airway disease for which accurate etiological diagnosis is crucial for effective management. A group of experts from the China Bronchiectasis Alliance and the Infection Assembly of the Chinese Thoracic Society conducted a comprehensive review of recent research into the etiology of bronchiectasis. Using the widely accepted Delphi methodology, the experts reached a consensus on the etiological diagnosis of bronchiectasis through multiple rounds of discussion and revision.
View Article and Find Full Text PDFDistal esophageal spasm and gastroesophageal reflux disease: re-examining the association.
Dis Esophagus
October 2024
Division of Gastroenterology and Hepatology at Mount Sinai West and Morningside, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Distal esophageal spasm (DES) is a rare motility disorder presenting with dysphagia or chest pain. Although studies suggest a link between DES and gastroesophageal reflux disease (GERD), data supporting a distinct GERD-related phenotype are limited. This study aims to investigate demographic, symptomatic, and physiologic differences between DES subjects with and without GERD.
View Article and Find Full Text PDFComparative evaluation of endoscopic anti-reflux mucosectomy and stretta radiofrequency ablation in the management of gastroesophageal reflux disease: insights from a retrospective multicenter cohort study.
Surg Endosc
August 2024
Division of Gastroenterology, Department of Internal Medicine, Cha Gangnam Medical Center, College of Medicine, Cha University, 566, Nonhyeon-Ro, Gangnam-Gu, Seoul, Republic of Korea.
Background: Treatment options for gastroesophageal reflux disease (GERD) that is unresponsive to proton pump inhibitors (PPIs) remain limited. Therefore, we compared the therapeutic effects of anti-reflux mucosectomy (ARMS) and Stretta radiofrequency (SRF) for intractable GERD in over 400 individuals who underwent either procedure.
Methods: We conducted a retrospective study between 2016 and 2023 to evaluate the effectiveness of SRF and ARMS treatments for refractory GERD.
The status quo of short video as sources of health information on gastroesophageal reflux disease in China: a cross-sectional study.
Front Public Health
June 2024
Department of Gastroenterology, Gaoxin Branch of The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Background: Positive lifestyle adjustments have become effective methods in treating gastroesophageal reflux disease (GERD). Utilizing short video platforms to encourage GERD patients for effective self-disease management is a convenient and cost-effective approach. However, the quality of GERD-related videos on short video platforms is yet to be determined, and these videos may contain misinformation that patients cannot recognize.
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