Our research tested two predictions regarding how likelihood can have motivational effects as a function of how a probability is . We predicted that describing the probability of a event that could be either A or B using the language of high likelihood ("80% A") rather than low likelihood ("20% B"), i.e., high rather than low likelihood, would make a activity more real and engaging, as long as the future event had properties relevant to the present activity. We also predicted that strengthening engagement from the high (. low) expressed likelihood of a future event would intensify the value of present positive and negative objects (in opposite directions). Both predictions were supported. There was also evidence that this intensification effect from expressed likelihood was independent of the actual probability or valence of the future event. What mattered was whether high versus low likelihood language was used to describe the future event.
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http://dx.doi.org/10.1016/j.joep.2012.03.005 | DOI Listing |
PLoS One
January 2025
Department of Cardiovascular and Metabolic Medicine, Faculty of Health and Life Sciences, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.
Introduction: New Onset Atrial Fibrillation (NOAF) is the most common arrhythmia in intensive care. Complications of NOAF include thromboembolic events such as myocardial infarction and stroke, which contribute to a greater risk of mortality. Inflammatory and coagulation biomarkers in sepsis are thought to be associated with NOAF development.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Université de Genève, Département de Physique Théorique and Gravitational Wave Science Center (GWSC), 24 quai Ernest Ansermet, 1211 Genève 4, Switzerland.
Joint gravitational-wave and γ-ray burst (GRB) observations are among the best prospects for standard siren cosmology. However, the strong selection effect for the coincident GRB detection, which is possible only for sources with small inclination angles, induces a systematic uncertainty that is currently not accounted for. We show that this severe source of bias can be removed by inferring the a priori unknown electromagnetic detection probability directly from multimessenger data.
View Article and Find Full Text PDFBreast Cancer
January 2025
Advanced Cancer Translational Research Institute, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Antibody-drug conjugates (ADCs) are an emerging class of anticancer therapy that combines the specificity and long circulation half-life of monoclonal antibodies with the cytotoxic potency of the payload connected through a chemical linker. The optimal management of toxicities is crucial for improving quality of life in patients undergoing ADCs and for avoiding improper dose reductions or discontinuations. This article focuses on the characteristics and management of nausea and vomiting (NV) induced by three ADCs: trastuzumab deruxtecan (T-DXd), sacituzumab govitecan (SG), and datopotamab deruxtecan (Dato-DXd).
View Article and Find Full Text PDFCrit Care Med
January 2025
Department of Surgery, Neurology and Neurosurgery Unit, Federal University of Góias, Góias, Brazil.
Objectives: Balancing oxygen requirements, neurologic outcomes, and systemic complications from transfusions in traumatic brain injury (TBI) patients is challenging. This review compares liberal and restrictive transfusion strategies in TBI patients.
Data Sources: Electronic databases were searched from inception to October 2024.
Elife
January 2025
Department of Cognitive Psychology, University of Hamburg, Hamburg, Germany.
When retrieved, seemingly stable memories can become sensitive to significant events, such as acute stress. The mechanisms underlying these memory dynamics remain poorly understood. Here, we show that noradrenergic stimulation after memory retrieval impairs subsequent remembering, depending on hippocampal and cortical signals emerging during retrieval.
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