Objective: To estimate the incremental delivery cost of human papillomavirus (HPV) vaccination of young adolescent girls in Peru, Uganda and Viet Nam.
Methods: Data were collected from a sample of facilities that participated in five demonstration projects for hpv vaccine delivery: school-based delivery was used in Peru, Uganda and Viet Nam; health-centre-based delivery was also used in Viet Nam; and integrated delivery, which involved existing health services, was also used in Uganda. Microcosting methods were used to guide data collection on the use of resources (i.e. staff, supplies and equipment) and data were obtained from government, demonstration project and health centre administrative records. Delivery costs were expressed in 2009 United States dollars (US$). Exclusively project-related expenses and the cost of the vaccine were excluded.
Findings: The economic delivery cost per vaccine dose ranged from US$ 1.44 for integrated outreach in Uganda to US$ 3.88 for school-based delivery in Peru. In Viet Nam, the lowest cost per dose was US$ 1.92 for health-centre-based delivery. Cost profiles revealed that, in general, the largest contributing factors were project start-up costs and recurrent personnel costs. The delivery cost of HPV vaccine was higher than published costs for traditional vaccines recommended by the Expanded Programme on Immunization (EPI).
Conclusion: The cost of delivering HPV vaccine to young adolescent girls in Peru, Uganda and Viet Nam was higher than that for vaccines currently in the EPI schedule. The cost per vaccine dose was lower when delivery was integrated into existing health services.
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http://dx.doi.org/10.2471/BLT.12.113837 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Institute of Plant Protection, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
The broader use of botanical pesticides has been limited by shorter residual activity on plants, slower onset of action, and higher costs compared with conventional pesticides. These challenges could be overcome by the development of simple, cost-effective, and long-lasting preventive nanocomposites for botanical pesticides. In this study, we successfully developed a low-cost ethyl cellulose (EC)-based delivery system for the botanical pesticide osthole (OST), designed to provide extended preventive protection against infestations.
View Article and Find Full Text PDFNiger Med J
January 2025
Department of Community Medicine, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State Nigeria.
Background: Choosing the appropriate place for delivery has a significant impact on the outcome of labour and childbirth. This study aimed to identify the factors associated with the place of delivery among women in Ogun East senatorial district, Nigeria.
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MedEdPORTAL
January 2025
Associate Professor, Internal Medicine, Oregon Health & Science University School of Medicine; Portland Veterans Administration Hospital.
Introduction: High-value cost-conscious care (HVCCC) education has been shown to reduce wasteful health care spending. Incorporating HVCCC into a medical school curriculum can be challenging due to limited curricular time. We explored the feasibility of medical students creating HVCCC peer education within existing platforms at a single urban academic medical school.
View Article and Find Full Text PDFExpert Opin Drug Deliv
January 2025
Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California, USA.
Introduction: Cyclic antimicrobial peptides (CAMPs) are gaining attention as promising candidates in advanced drug delivery systems due to their structural stability, resistance to proteolytic degradation, and versatile therapeutic potential. Their unique properties enable applications that extend beyond combating multidrug-resistant (MDR) pathogens. Their amphipathic and cell-penetrating properties allow them to efficiently transport drugs across cellular membranes.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Department of Engineering, University Campus Bio-Medico of Rome, Via Alvaro del Portillo 21, Rome, 00128, Italy.
Background: Oxygen therapy is critical and vital treatment for hypoxemia and respiratory distress, however, access to reliable oxygen systems remains limited in SSA. Despite WHO initiatives that distributed over 30,000 OC oxygen concentrators worldwide, SSA faces significant challenges related to their maintenance and use, due to harsh environmental conditions, technical skill shortages and inadequate infrastructure. This review aims to systematically identify and assess the literature on OC design adaptations, maintenance challenges, and knowledge gaps in SSA, providing actionable recommendations to inform innovative and context-sensitive solutions to improve healthcare delivery in the region.
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