High-power fiber lasers operating at the 1.5 μm wavelength region have attractive features, such as eye safety and atmospheric transparency, and cascaded Raman fiber lasers offer a convenient method to obtain high-power sources at these wavelengths. A limitation to power scaling, however, has been the lower conversion efficiency of these lasers. We recently introduced a high-efficiency architecture for high-power cascaded Raman fiber lasers applicable for 1.5 μm fiber lasers. Here we demonstrate further power scaling using this new architecture. Using numerical simulations, we identify the ideal operating conditions for the new architecture. We demonstrate a high-efficiency 1480 nm cascaded Raman fiber laser with an output power of 301 W, comparable to record power levels achieved with rare-earth-doped fiber lasers in the 1.5 μm wavelength region.
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http://dx.doi.org/10.1364/OL.38.002538 | DOI Listing |
Toxins (Basel)
November 2024
Institut des Neurosciences Paris-Saclay, UMR 9197, CNRS/Université Paris-Sud, 91198 Gif-sur-Yvette, Cedex, France.
Botulinum neurotoxin type-A (BoNT/A), which blocks quantal acetylcholine (ACh) release at the neuromuscular junction (NMJ), has demonstrated its efficacy in the symptomatic treatment of blepharospasm. In 3.89% of patients treated for blepharospasm at Tenon Hospital, BoNT/A was no longer effective in relieving the patient's symptoms, and a partial upper myectomy of the muscle was performed.
View Article and Find Full Text PDFBiosensors (Basel)
December 2024
Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), Shenzhen 518107, China.
The demand for non-invasive, real-time health monitoring has driven advancements in wearable sensors for tracking biomarkers in sweat. Ammonium ions (NH) in sweat serve as indicators of metabolic function, muscle fatigue, and kidney health. Although current ion-selective all-solid-state printed sensors based on nanocomposites typically exhibit good sensitivity (~50 mV/log [NH]), low detection limits (LOD ranging from 10 to 10 M), and wide linearity ranges (from 10 to 10 M), few have reported the stability test results necessary for their integration into commercial products for future practical applications.
View Article and Find Full Text PDFAm J Physiol Cell Physiol
December 2024
Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Plasma membrane repair (PMR) restores membrane integrity of cells, preventing cell death in vital organs, and has been studied extensively in skeletal muscle. Dysferlin, a sarcolemmal Ca-binding protein, plays a crucial role in PMR in skeletal muscle. Previous studies have suggested that PMR employs membrane trafficking and membrane fusion, similar to neurotransmission.
View Article and Find Full Text PDFUrology
December 2024
Division of Urology, Department of Surgery, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Objectives: To investigate the effectiveness of different holmium:yttrium-aluminum-garnet (Ho:YAG) laser modes for lithotripsy in the "dusting era" and identify the optimal laser mode for producing stone fragments measuring ≤0.5 mm.
Methods: We used plaster of Paris-made artificial stones crushed into 2-3 mm pieces, weighing 1 g in total.
J Cancer Res Clin Oncol
December 2024
Department of Neurosurgery, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Purpose: Analysis of autofluorescence holds promise for brain tumor delineation and diagnosis. Therefore, we investigated the potential of a commercial confocal laser scanning endomicroscopy (CLE) system for clinical imaging of brain tumors.
Methods: A clinical CLE system with fiber probe and 488 nm laser excitation was used to acquire images of tissue autofluorescence.
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