Purpose: To study microdistortions in Bowman's layer after femtosecond laser small incision lenticule extraction (SMILE) using Fourier-domain optical coherence tomography (OCT) and to investigate possible sources and potential visual impacts.
Methods: A nonrandomized controlled prospective study enrolled 52 eyes of 29 consecutive patients undergoing SMILE, with spherical equivalent of -6.33 ± 1.88 diopters and 4.2 mm superior incision. The microdistortions in Bowman’s layer were counted at 1 day, 1 week, and 1 month postoperatively and at long-term follow-up. Another 38 eyes of 20 patients undergoing femtosecond laser-assisted LASIK (FS-LASIK) were examined at 1 day and long-term postoperatively as the control group.
Results: Microdistortions in Bowman’s layer were observed by OCT, with no clinically significant corneal striae under slit-lamp microscopy, in 46 eyes (88.5%) on day 1 after SMILE and in 16 eyes (42.1%) after FS-LASIK, with more in SMILE eyes than in FS-LASIK eyes. The amount decreased at 1 week and then remained stable. There were more microdistortions in the center area than in the periphery in both groups. Microdistortions were more in the inferior than the superior quadrant on the first day after SMILE but there was no difference at long-term follow-up. Microdistortions after SMILE were associated with the refractive lenticule thickness and surgery order but had no significant impact on long-term visual outcomes or wavefront aberrations.
Conclusions: Microdistortions in Bowman's layer after SMILE were associated with the refractive lenticule thickness and surgery order. The microdistortions remained stable after 1 week and had no impact on long-term visual performance.
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http://dx.doi.org/10.3928/1081597X-20130806-01 | DOI Listing |
Front Med (Lausanne)
April 2022
Department of Ophthalmology, Eye Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Purpose: To evaluate the outcomes in corneal higher-order aberrations (HOAs) and microdistortions in the Bowman's layer after femtosecond laser small incision lenticule extraction (SMILE) for correcting extremely high myopia.
Methods: This prospective study included patients with myopia with spherical equivalent ≥ -9.0 Diopters (D).
BMC Ophthalmol
June 2019
Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China Shanghai Research Center of Ophthalmology and Optometry, NHC Key Laboratory of Myopia, Shanghai, People's Republic of China.
Background: This study compares the clinical outcomes of femtosecond laser small-incision lenticule extraction (SMILE) for the correction of myopia and myopic astigmatism greater than - 10 D, and - 10 D or less respectively.
Methods: 60 eyes/patients were equally selected into group 1 (myopia and myopic astigmatism of - 10 D or less) and group 2 (myopia and myopic astigmatism of over - 10 D), both of which were treated with SMILE. Visual and refractive outcomes, corneal higher-order aberrations, and Bowman's layer micro-distortions were evaluated preoperatively, 3 months, and 6 months postoperatively.
Purpose: To investigate the characteristics and changes in microdistortions in Bowman's layer 3 years after small incision lenticule extraction (SMILE).
Methods: In this non-randomized, prospective study, 50 eyes of 28 patients who received SMILE with a mean spherical equivalent of -6.72 ± 1.
Invest Ophthalmol Vis Sci
November 2018
Imaging, Biomechanics and Mathematical Modeling Solutions Lab, Narayana Nethralaya Foundation, Bangalore, India.
Purpose: To simulate deformation amplitude after laser-assisted in situ keratomileusis (LASIK), small incision lenticule extraction (SMILE), and photorefractive keratectomy (PRK) with finite element models.
Methods: Finite element simulations of air-puff applanation on LASIK, SMILE, and PRK models were performed on a cohort of normal eyes, which had undergone refractive treatments. Short- and long-term wound healing responses were considered for SMILE and LASIK models based on evidence of microdistortions in Bowman's layer and crimping of collagen fibers.
Purpose: To investigate changes in intraocular scattering and Bowman's layer microdistortions after femtosecond laser small incision lenticule extraction using the continuous curvilinear lenticulerhexis technique (SMILE-CCL).
Methods: In this prospective study, 93 eyes of 93 patients (44 women, 49 men) were treated with SMILE-CCL. Mean age was 26.
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