The methodology of testing antiaging drugs in laboratory mice is presented. It is based on more than 40-year-long authors' experience in the field and includes the selection of mouse strain, sex, age at start of treatment, housing conditions, design of the long-term study, some noninvasive methods of assessment of biomarkers of aging, life-span parameters, pathology examination, and statistical treatment of the results.
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| http://dx.doi.org/10.1007/978-1-62703-556-9_12 | DOI Listing |
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