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Investigating the Gene Relation Between Cervical Spondylosis and Depression: Bidirectional Mendelian Randomization Study.
J Pain Res
December 2024
The Affiliated Hospital of Guizhou Medical University, Guiyang, People's Republic of China.
Background: Previous observational studies have suggested a potential link between depression and cervical spondylosis (CS). While it is known that depression and CS can coexist, the specific relationship between them is not fully understood. We hypothesize that there may be connections between the two conditions, but the independent causal relationship of depression as a risk factor for CS, remains uncertain.
View Article and Find Full Text PDFEffectively addressing ethical issues in precision medicine research in Africa requires a holistic social contract that integrates biomedical knowledge with local cultural values and Indigenous knowledge systems. Drawing on African epistemologies such as ubuntu and ujamaa and on our collective experiences in genomics and big data research for sickle cell disease, hearing impairment, and fragile X syndrome and the project Public Understanding of Big Data in Genomics Medicine in Africa, we envision a transformative shift in health research data governance in Africa that could help create a sense of shared responsibility between all stakeholders in genomics and data-driven health research in Africa. This shift includes proposing a social contract for genomics and data science in health research that is grounded in African communitarianism such as solidarity, shared decision-making, and reciprocity.
View Article and Find Full Text PDFLongitudinal analysis of academic stress and its effects on salivary cortisol, alpha-amylase, and academic outcomes: Study protocol.
PLoS One
December 2024
Programa de Neurociencia, Psiquiatría y Salud Mental, NEPSAM, Universidad de Concepción, Concepción, Chile.
Introduction: Academic stress is a prevalent problem among university students, affecting both their psychological well-being and academic performance. This study aims to investigate the mediating roles of biological and psycho-behavioural variables in the relationship between academic stress and academic performance over the course of a semester. Through a longitudinal approach and using accessible data collection technologies, the results will enable the design of effective interventions to mitigate the impact of academic stress.
View Article and Find Full Text PDFThe Australian clinical trial landscape: Perceptions of rural, regional and remote health service capacity and capability.
Health Res Policy Syst
December 2024
College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia.
Background: Access to clinical trials is limited for rural, regional and remote Australians, adding to the current health inequity between rural and metropolitan populations. The Australasian Teletrial Model was developed to bring clinical trials "closer to home". In 2020, the Australian Teletrial Program was funded to expand and support the uptake of the model across six Australian states and territories.
View Article and Find Full Text PDFStudents' experiences of placements in urban indigenous health contexts: developing a culturally responsive workforce.
BMC Med Educ
December 2024
The Burnet Institute, Melbourne, Australia.
Background: A culturally responsive health workforce is essential to ensure the delivery of culturally safe health services that meet Aboriginal and Torres Strait Islander Peoples needs. In partnership with universities, placement providers play an essential role in creating opportunities for immersive experiences that enable students to develop their cultural responsiveness. This study evaluated students' experiences of an innovative student placement model embedded within an urban Aboriginal and Torres Strait Islander Community-Controlled Health Organisation.
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