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Measurement of the Vaginal Pressure Profile with the Femfit® and Leakage Events Using a Newly Developed Pad Test during Selected Sports Activities: A Pilot Study.
Int Urogynecol J
January 2025
Department of Urology, Institution - Jessenius Faculty of Medicine, Comenius University Bratislava, Martin, Slovak Republic.
Introduction And Hypothesis: Measuring changes in the vaginal pressure profile (VPP) with the Femfit® by JUNOFEM during various sports will help improve understanding of the magnitude of pressures generated during such activities and the pelvic floor's response to those pressures. This could aid in selecting safe exercises for women with pelvic floor dysfunction. The primary aim of this study was to measure intravaginal pressure changes using a novel pressure sensor array (Femfit®) during high-risk sports activities in elite female athletes with and without stress urinary incontinence (SUI).
View Article and Find Full Text PDFEffectiveness of an intensive outpatient treatment programme combining prolonged exposure and EMDR therapy for adolescents and young adults with PTSD in a naturalistic setting.
Eur J Psychotraumatol
December 2025
Altrecht Academic Anxiety Center, Altrecht GGZ, Utrecht, the Netherlands.
Psychotherapeutic interventions aimed at treating posttraumatic stress disorder (PTSD) in adolescents and young adults are hampered by high dropout rates. Looking at the results from adult treatments, short, intensive, outpatient treatment programmes may offer a promising alternative, but it has yet to be tested in this young population. To assess the results of a six-day intensive outpatient trauma-focused treatment programme for young individuals (12-25 years) with PTSD.
View Article and Find Full Text PDFTiming for a surgically safe and oncologically prompt pancreatoduodenectomy after preoperative biliary drainage in patients with bile duct cancer.
ANZ J Surg
January 2025
Division of Hepatobiliary-Pancreatic Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.
Background: Preoperative biliary drainage (PBD) is commonly performed in patients with bile duct cancer (BDC). However, data regarding the timing of pancreatoduodenectomy (PD) after PBD are insufficient. This study aimed to investigate the optimal timing for surgically and oncologically safe PD after PBD.
View Article and Find Full Text PDFDeveloping a co-designed, culturally responsive physical activity program for Pasifika communities in Western Sydney, Australia.
Health Promot Int
January 2025
Human Performance Research Centre, School of Sport, Exercise, and Rehabilitation, Faculty of Health, University of Technology Sydney (UTS), Moore Park Rd, Moore Park, Gadigal Land, Eora Nation, Sydney, New South Wales, 2021, Australia.
Pasifika communities in Western Sydney experience significant health disparities, particularly related to chronic diseases such as cardiovascular conditions and diabetes. Physical activity is known to improve both physical and mental health, yet access to culturally responsive physical activity programs for Pasifika communities is limited. This study leveraged expertise from an Advisory Committee to adopt community-based participatory research (CBPR) through Talanoa to co-design a physical activity program specifically tailored for Pasifika people in Western Sydney.
View Article and Find Full Text PDFSyngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases.
Elife
January 2025
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Natural killer (NK) cells can control metastasis through cytotoxicity and IFN-γ production independently of T cells in experimental metastasis mouse models. The inverse correlation between NK activity and metastasis incidence supports a critical role for NK cells in human metastatic surveillance. However, autologous NK cell therapy has shown limited benefit in treating patients with metastatic solid tumors.
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