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A Preliminary Phenomenological Exploration of Experiences of the Empty Pelvis Syndrome Derived From a Modified-Delphi: The Price of Survival Following Pelvic Exenteration for Advanced Pelvic Cancer.
Psychooncology
October 2024
Health Sciences, University of Southampton, Southampton, UK.
Objective: The empty pelvis syndrome (EPS) is common after pelvic exenteration (PE), causing fluid collections, bowel obstruction, perineal sinuses, and fistulas. The best approach to fill the pelvis to mitigate this remains controversial, and the impact of EPS on health-related quality of life (HrQoL) is unknown. This study is the first to begin to explore lived-experiences of EPS complications.
View Article and Find Full Text PDFOrgan dose equivalents of albedo protons and neutrons under exposure to large solar particle events during lunar human landing missions.
Life Sci Space Res (Amst)
August 2024
Department of Health Physics and Diagnostic Sciences, School of Integrated Health Sciences, University of Nevada, Las Vegas, NV 89154, USA. Electronic address:
Astronauts participating in lunar landing missions will encounter exposure to albedo particles emitted from the lunar surface as well as primary high-energy particles in the spectra of galactic cosmic rays (GCRs) and solar particle events (SPEs). While existing studies have examined particle energy spectra and absorbed doses in limited radiation exposure scenarios on and near the Moon, comprehensive research encompassing various shielding amounts and large SPEs on the lunar surface remains lacking. Additionally, detailed organ dose equivalents of albedo particles in a human model on the lunar surface have yet to be investigated.
View Article and Find Full Text PDFTissue-specific dose equivalents of secondary mesons and leptons during galactic cosmic ray exposures for mars exploration.
Life Sci Space Res (Amst)
May 2024
Department of Health Physics and Diagnostic Sciences, School of Integrated Health Sciences, University of Nevada, Las Vegas, NV 89154, United States. Electronic address:
During a human mission to Mars, astronauts would be continuously exposed to galactic cosmic rays (GCR) consisting of high energy protons and heavier ions coming from outside our solar system. Due to their high energy, GCR ions can penetrate spacecraft and space habitat structures, directly reaching human organs. Additionally, they generate secondary particles when interacting with shielding materials and human tissues.
View Article and Find Full Text PDFCalculation of dose distribution in a realistic brain structure and the indication of space radiation influence on human brains.
Life Sci Space Res (Amst)
November 2020
Institute of Experimental and Applied Physics, University of Kiel, Kiel, DE24118, Germany.
One of the most important steps in the near-future space age will be a crew mission returning to the Moon and even a manned mission to Mars. Unfortunately, such a mission will expose astronauts to unavoidable cosmic radiation in deep space and on the Martian or lunar surface. Thus, a better understanding of the radiation environment for such a mission and the consequent biological impacts on humans, in particular the human brains, is critical.
View Article and Find Full Text PDFClinical implementation of PLANET® Dose for dosimetric assessment after [Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0.
EJNMMI Res
January 2021
Nuclear Medicine Department, Montpellier Cancer Institute (ICM), Univ. Montpellier, 208 Avenue des Apothicaires, 34298, Montpellier Cedex 5, France.
Background: The aim of this study was to compare a commercial dosimetry workstation (PLANET® Dose) and the dosimetry approach (GE Dosimetry Toolkit® and OLINDA/EXM® V1.0) currently used in our department for quantification of the absorbed dose (AD) to organs at risk after peptide receptor radionuclide therapy with [Lu]Lu-DOTA-TATE.
Methods: An evaluation on phantom was performed to determine the SPECT calibration factor variations over time and to compare the Time Integrated Activity Coefficients (TIACs) obtained with the two approaches.
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