The implications of cocaine use during pregnancy include an increased incidence of stillbirths, abruptio placentae, and an increased risk of other delivery complications. The neonate born to a woman using cocaine may show a lack of definite physical stigmata, absence of consistent withdrawal patterns, and high incidence of irritability during the neonatal period. Nursing implications for promoting optimal pregnancy and neonatal outcome primarily involve early pregnancy intervention, consistent care, education, and delivery management. During the neonatal period, the nurse should work to reduce stimulation, position to promote optimal interaction, educate the parents, and initiate follow-up care for continued developmental assessments. At this time, available data merely suggest associations between cocaine use and negative perinatal outcomes; they do not imply causal relationships. Because the adverse effects to the fetus and newborn are not conclusively documented in the literature, it can be difficult to educate the preconceptual or pregnant woman about the risks of cocaine use during pregnancy. Despite this obstacle, the nurse must use the information available to present as clear a picture as possible of the risks of exposing the fetus to cocaine.
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Medicine (Baltimore)
October 2024
Mardin Artuklu University Faculty of Medicine, Obstetrics and Gynecology, Mardin, Turkey.
Background: The aim of this study was to determine whether orexigenic neuropeptides, orexin and galanin, and anorexigenic neuropeptides, alpha-melanocyte-stimulating hormone (α-MSH) and cocaine- and amphetamine-regulated transcript (CART), are implicated in hyperemesis gravidarum (HG).
Methods: Fifty pregnant women who had been diagnosed with HG between April 2022 and February 2023 at the Siirt University Faculty of Medicine Training and Research Hospital (tertiary center) were recruited for this study. An equal number of pregnant women without an HG diagnosis were included in the study as the control group.
Child Maltreat
October 2024
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Int J Dev Neurosci
October 2024
Subdirección de Investigaciones Clínicas, Laboratorio de Neurofarmacología Conductual, Microcirugía y Terapéutica Experimental, Instituto Nacional de Psiquiatría, Mexico City, Mexico.
Contemp Clin Trials Commun
October 2024
Program for Addiction Research, Clinical Care, Knowledge and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, 295 Chipeta Way, Salt Lake City, UT, USA.
Background: While most pregnant individuals with methamphetamine use disorder (MUD) achieve abstinence, the postpartum period remains a vulnerable time for return to methamphetamine use (MU). Promising data from human and animal models, including three randomized controlled trials, suggest that micronized progesterone may prevent postpartum return to cocaine and nicotine use by reducing cravings. The primary objective of this study is to assess feasibility of enrollment and randomization of postpartum individuals with MUD to micronized progesterone to prevent return to MU.
View Article and Find Full Text PDFBehav Pharmacol
October 2024
College of Biological Sciences and Engineering, North Minzu University, Yinchuan, Ningxia, China.
Increasing evidence indicates that prenatal cocaine exposure may result in many developmental and long-lasting neurological and behavioral effects. The behaviors of female animals are strongly associated with the estrous cycle. Estrogen receptors and oxytocin are important neuroendocrine factors that regulate social behavior and are of special relevance to females.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!