A novel Pd(0)-catalyzed sequential C-N bond formation process via allylic and aromatic C-H amination of α-methylstyrenes with di-tert-butyldiaziridinone, giving spirocyclic indolines in good yields, is described. Four C-N bonds and one spiro quaternary carbon are generated in a single operation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864675 | PMC |
| http://dx.doi.org/10.1021/ol401935c | DOI Listing |
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