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http://dx.doi.org/10.1016/j.eururo.2013.06.030 | DOI Listing |
Health Care Anal
January 2025
Department of General Practice and Primary Health Care, University of Auckland, Private Bag 92019, Auckland, New Zealand.
This paper questions the conventional wisdom that physicians must suppress anger in response to patient misbehaviour. It distinguishes the emotion of anger from its expression, which leans toward concerned frustration and disappointment for the sake of professionalism in patient care. Drawing on the framework of person-centred health care as a virtue ethic, the paper first suggests four reasons why and when physician anger toward patient behaviour may occasionally be appropriate: the inevitability of sometimes feeling angry, anger as a cognitive and behavioural resource, physician well-being, and potential patient benefit.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Earth and Environment, Institute of Environment, Florida International University, Miami, FL, USA.
Anal Bioanal Chem
December 2024
XJTLU Wisdom Lake Academy of Pharmacy-BEAVER Biomedical Joint Laboratory, Suzhou, 215123, China.
Protein glycosylation is one of the most important post-translational modifications, implicated in the development of various diseases, including neurodegenerative diseases, diabetes, and cancers. However, the low content of glycoproteins in biological samples, the diversity and heterogeneity of glycan structures, and insensitive detection methods make glycosylation analysis challenging. As a result, efficient enrichment of glycopeptides from complex samples is a critical step.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Laboratory of Animal Genetics, Department of Veterinary and Biosciences, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Assessing the pathogenicity of a disease-associated genetic variant in animals accurately is vital, both on a population and individual scale. At the population level, breeding decisions based on invalid DNA tests can lead to the incorrect inclusion or exclusion of animals and compromise the long-term health of a population, and at the level of the individual animal, lead to incorrect treatment and even life-ending decisions. Criteria to determine pathogenicity are not standardized, i.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
November 2024
School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 102488, China Traditional Chinese Medicine Processing Technology Inheritance Base of National Administration of Traditional Chinese Medicine Beijing 102488, China Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica Beijing 102488, China.
The processing of traditional Chinese medicine(TCM) is a core theory within TCM, embodying deep philosophical, cultural, and natural scientific wisdom. Among the various techniques, the "synergistic processing of medicinal materials and excipients" has garnered significant attention due to its uniqueness. This study explored the impact of the adjuvant Glycyrrhizae Radix et Rhizoma on the dynamic process of component transformation during the processing of Aconiti Lateralis Radix Praeparata using techniques such as acidic dye colorimetry, UPLC-Q-TOF-MS/MS, density functional theory(DFT), and molecular dynamics simulations(MDS).
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