Drug delivery approaches for ovarian cancer therapy.

Methods Mol Biol

Laboratory of Oncoendocrinology, NN Petrov Institute of Oncology, St. Petersburg, Russia.

Published: March 2014

Tumor-specific drug delivery represents a challenging issue that restricts the clinical applications of many advanced anticancer therapeutics. Ovarian cancer exhibits a quite specific pattern of dissemination: it spreads primarily within the peritoneal cavity, providing a possibility of locoregional, intraperitoneal drug administration. Considering this unique aspect of ovarian cancer biology, this chapter provides a short review of most promising approaches for therapeutic delivery of genetic drugs.

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http://dx.doi.org/10.1007/978-1-62703-547-7_33DOI Listing

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